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2012 Fiscal Year Final Research Report

Development of systems with endoscopic ultrasonography for diagnosis and treatment of bilio-pancreatic diseases

Research Project

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Project/Area Number 22590764
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Gastroenterology
Research InstitutionKinki University

Principal Investigator

KITANO Masayuki  近畿大学, 医学部, 准教授 (50314571)

Co-Investigator(Kenkyū-buntansha) KUDO Masatoshi  近畿大学, 医学部, 教授 (10298953)
NISHIO Kazuto  近畿大学, 医学部, 教授 (10208134)
Project Period (FY) 2010 – 2012
Keywords超音波内視鏡学 / 膵臓病学 / 検査診断システム
Research Abstract

The usefulness of contrast-enhanced harmonic endoscopic ultrasonography for characterization of solid tumors in the pancreas, characterization of intra-abdominal lesions of undetermined origin and estimation of malignant potential of gastrointestinal stromal tumors was evaluated. In comparison with the other imaging methods, this novel technique improved the diagnostic ability for these diseases. Endoscopic ultrasonography guided broad plexus neurolysis achieved better pain relief than endoscopic ultrasonography guided celiac plexus neurolysis. Development of endoscopic ultrasonography guided drainage allowed salvage drainage treatment for obstruction of bilio-pancreatic system after unsuccessful transpapillary or surgical drainage.

  • Research Products

    (34 results)

All 2013 2012 2011 2010

All Journal Article (15 results) (of which Peer Reviewed: 15 results) Presentation (15 results) Book (4 results)

  • [Journal Article] Characterization of small solid tumors in the pancreas: the value of contrast-enhanced harmonic endoscopic ultrasonography2012

    • Author(s)
      Kitano M, Kudo M, Yamao K, Takagi T, Sakamoto H, Komaki T, Kamata K, Imai H, Chiba Y, Okada M, Murakami T, Takeyama Y
    • Journal Title

      American Journal of Gastroenterology

      Volume: 107 Pages: 303-310

    • DOI

      DOI: 10.1038/ajg.2011.354.

    • Peer Reviewed
  • [Journal Article] Plasma concentrations of angiogenesis-related molecules in patients with pancreatic cancer2012

    • Author(s)
      Sakamoto H, Kimura H, Sekijima M, Matsumoto K, Arao T, Chikugo T, Yamada Y, Kitano M, Ito A, Takeyama Y, Kudo M, Nishio K
    • Journal Title

      Japanese Journal of Clinical Oncology

      Volume: 42 Pages: 105-112

    • DOI

      DOI: 10.1093/jjco/hyr178.

    • Peer Reviewed
  • [Journal Article] Endoscopic ultrasound: contrast enhancement2012

    • Author(s)
      Kitano M, Sakamoto H, Kudo M
    • Journal Title

      Gastrointestinal Endoscopy Clinics of North America

      Volume: 22 Pages: 349-358

    • DOI

      DOI: 10.1016/j.giec.2012.04.013.

    • Peer Reviewed
  • [Journal Article] Transcatheter endoscopy for pancreaticobiliary duct diseases (with videos)2012

    • Author(s)
      Sakamoto H, Kitano M, Kamata K, Miyata T, Kadosaka K, Imai H, Takeyama Y, Kudo M
    • Journal Title

      Gastrointestinal Endoscopy

      Volume: 76 Pages: 892-899

    • DOI

      DOI: 10.1016/j.gie.2012.06.012.

    • Peer Reviewed
  • [Journal Article] Estimation of malignant potential of GI stromal tumors by contrast-enhanced harmonic EUS (with videos)2011

    • Author(s)
      Sakamoto H, Kitano M, Matsui S, Kamata K, Komaki T, Imai H, Dote K, Kudo M
    • Journal Title

      Gastrointestinal Endoscopy

      Volume: 73 Pages: 227-37

    • DOI

      DOI: 10.1016/j.gie.2010.10.011.

    • Peer Reviewed
  • [Journal Article] Endoscopic ultrasonography and contrast-enhanced endoscopic ultrasonography2011

    • Author(s)
      Kitano M, Kudo M, Sakamoto H, Komaki T
    • Journal Title

      Pancreatology

      Volume: 11 Suppl 2 Pages: 28-33

    • DOI

      DOI: 10.1159/000323493.

    • Peer Reviewed
  • [Journal Article] Endoscopic ultrasonography-guided biliary drainage: evaluation of a choledochoduodenostomy technique2011

    • Author(s)
      Komaki T, Kitano M, Sakamoto H, Kudo M
    • Journal Title

      Pancreatology

      Volume: 11 Suppl 2 Pages: 47-51

    • DOI

      DOI: 10.1159/000323508.

    • Peer Reviewed
  • [Journal Article] Endoscopic ultrasound-guided neurolysis in pancreatic cancer2011

    • Author(s)
      Sakamoto H, Kitano M, Komaki T, Imai H, Kamata K, Kudo M
    • Journal Title

      Pancreatology

      Volume: 11 Suppl 2 Pages: 52-58

    • DOI

      DOI: 10.1159/000323513.

    • Peer Reviewed
  • [Journal Article] New techniques and future perspective of EUS for the differential diagnosis of pancreatic malignancies: contrast harmonic imaging2011

    • Author(s)
      Kitano M, Sakamoto H, Komaki T, Kudo M
    • Journal Title

      Digestive Endoscopy

      Volume: 23 Suppl 1 Pages: 46-50

    • DOI

      DOI:10.1111/j.1443-1661.2011.01146.x.

    • Peer Reviewed
  • [Journal Article] Pancreatic ductal drainage by endoscopic ultrasound-assisted rendezvous technique for pain caused by ductal stricture with chronic pancreatitis.2010

    • Author(s)
      Das K, Kitano M, Komaki T, Sakamoto H, Noda K, Suetomi Y, Kudo M
    • Journal Title

      Digestive Endoscopy

      Volume: 22 Pages: 217-219

    • DOI

      DOI:10.1111/j.1443-1661.2010.00980.x.

    • Peer Reviewed
  • [Journal Article] Characterization of intra-abdominal lesions of undetermined origin by contrast-enhanced harmonic EUS (with videos)2010

    • Author(s)
      Xia Y, Kitano M, Kudo M, Imai H, Kamata K, Sakamoto H, Komaki T
    • Journal Title

      Gastrointestinal Endoscopy

      Volume: 72 Pages: 637-642

    • DOI

      DOI: 10.1016/j.gie.2010.04.013.

    • Peer Reviewed
  • [Journal Article] Diagnosis of pancreatic tumors by endoscopic ultrasonography2010

    • Author(s)
      Sakamoto H, Kitano M, Kamata K, El-Masry M, Kudo M
    • Journal Title

      World Journal of Radiology

      Volume: 28 Pages: 122-134

    • DOI

      DOI: 10.4329/wjr.v2.i4.122.

    • Peer Reviewed
  • [Journal Article] Diagnosis of subepithelial tumors in the upper gastrointestinal tract by endoscopic ultrasonography2010

    • Author(s)
      Sakamoto H, Kitano M, Kudo M
    • Journal Title

      World Journal of Radiology

      Volume: 28 Pages: 289-297

    • DOI

      DOI: 10.4329/wjr.v2.i8.289.

    • Peer Reviewed
  • [Journal Article] Endoscopic ultrasound (EUS)-guided transluminal endoscopic removal of gallstones2010

    • Author(s)
      Kamata K, Kitano M, Kudo M, Imai H, Sakamoto H, Komaki T
    • Journal Title

      Endoscopy

      Volume: 42 Suppl 2 Pages: E331-332

    • DOI

      DOI: 10.1055/s-0030-1255941.

    • Peer Reviewed
  • [Journal Article] EUS-guided broad plexus neurolysis over the superior mesenteric artery using a 25-gauge needle2010

    • Author(s)
      Sakamoto H, Kitano M, Kamata K, Komaki T, Imai H, Chikugo T, Takeyama Y, Kudo M
    • Journal Title

      American Journal of Gastroenterology

      Volume: 105 Pages: 2599-2606

    • DOI

      DOI: 10.1038/ajg.2010.339.

    • Peer Reviewed
  • [Presentation] Therapeutic EUS - expanding horizons (Invited lecture)2013

    • Author(s)
      Kitano M
    • Organizer
      14th Annual Conference of Society of Gastrointestinal Endoscopy in India
    • Place of Presentation
      Gurgaon, India
    • Year and Date
      20130301-03
  • [Presentation] Contrast enhanced EUS & elastography (Invited lecture)2012

    • Author(s)
      Kitano M
    • Organizer
      The 6th Meeting of the Society of Gastrointestinal Intervention
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      20121005-06
  • [Presentation] Better imaging, better diagnosis? (Invited lecture)2012

    • Author(s)
      Kitano M
    • Organizer
      18th International Symposium on Endoscopic Ultrasonography
    • Place of Presentation
      Saint Petersburg, Russia
    • Year and Date
      20120906-08
  • [Presentation] Drastic improvement of patency of covered self-expandable metal stents for distal billiary obstruction caused by pancreatic carcinomas: a randomized multicenter study comparing covered and uncovered stents2012

    • Author(s)
      Kitano M
    • Organizer
      Digestive Disease Week 2012
    • Place of Presentation
      San Diego、USA
    • Year and Date
      20120519-22
  • [Presentation] EUS-guided drainage for biliary obstruction after unsuccessful ERCP2012

    • Author(s)
      Kitano M
    • Organizer
      第83回日本消化器内視鏡学会総会
    • Place of Presentation
      東京
    • Year and Date
      20120512-14
  • [Presentation] 造影ハーモニックEUS システムの開発と臨床応用2011

    • Author(s)
      北野雅之
    • Organizer
      第81回日本消化器内視鏡学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      20110817-19
  • [Presentation] Contrast-enhance harmonic EUS in diagnosing pancreatic neoplasms2011

    • Author(s)
      Kitano M
    • Organizer
      第81回日本消化器内視鏡学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      20110817-19
  • [Presentation] EUS-guided gallbladder drainage as an alternative treatment for malignant biliary obstruction after unsuccessful ERCP: Outcomes of long term follow-up2011

    • Author(s)
      Kitano M
    • Organizer
      Digestive Disease Week 2011
    • Place of Presentation
      Chicago、USA
    • Year and Date
      20110507-10
  • [Presentation] Characterization of small pancreatic neoplasms by contrast-enhanced harmonic EUS2010

    • Author(s)
      Kitano M
    • Organizer
      18th United European Gastroenterology Week
    • Place of Presentation
      Barcelona、Spain
    • Year and Date
      20101023-27
  • [Presentation] EUS ガイド下治療のコツと工夫2010

    • Author(s)
      北野雅之
    • Organizer
      第80回日本消化器内視鏡学会総会
    • Place of Presentation
      横浜
    • Year and Date
      20101013-16
  • [Presentation] Contrast-enhanced harmonic endosonography in diagnosing pancreatic diseases2010

    • Author(s)
      Kitano M
    • Organizer
      Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      20100711-13
  • [Presentation] 膵疾患に対する超音波内視鏡ガイド下ドレナージ術2010

    • Author(s)
      北野雅之
    • Organizer
      日本超音波医学会 第83回学術集会
    • Place of Presentation
      京都
    • Year and Date
      20100529-31
  • [Presentation] Contrast-enhanced harmonic EUS for diagnosis of pancreatic tumors2010

    • Author(s)
      Kitano M
    • Organizer
      第79回日本消化器内視鏡学会総会
    • Place of Presentation
      東京
    • Year and Date
      20100513-15
  • [Presentation] EUS-guided choledochoduodenostomy followed by endoscopic antegrade biliary stenting via the fistula for treatment of obstructive jaundice with duodenal stenosis2010

    • Author(s)
      Kitano M
    • Organizer
      Digestive Disease Week 2010
    • Place of Presentation
      New Orleans、USA
    • Year and Date
      20100501-05
  • [Presentation] EUS-guided gallbladder drainage for treatment of acute cholecystitis and obstructive jaundice2010

    • Author(s)
      Kitano M
    • Organizer
      Digestive Disease Week 2010
    • Place of Presentation
      New Orleans、USA
    • Year and Date
      20100501-05
  • [Book] Interventional EUS の極意「EUS-GBD のコツ」. 胆膵内視鏡治療-手技の極意とトラブルシューティング(分担執筆)2012

    • Author(s)
      北野雅之
    • Total Pages
      148-151
    • Publisher
      羊土社
  • [Book] 超音波内視鏡ガイド下穿刺術. 消化器内視鏡ハンドブック(分担執筆)2012

    • Author(s)
      北野雅之, 他
    • Total Pages
      111-122
    • Publisher
      日本メディカルセンター
  • [Book] 拡張膵管に対する治療. EUS 下穿刺術-Interventional EUS の基礎と実践テクニック-(分担執筆)2011

    • Author(s)
      北野雅之
    • Total Pages
      157-163
    • Publisher
      南江堂
  • [Book] 膵癌の診断と治療方針・疼痛対策. 今日の消化器疾患治療指針(分担執筆)2010

    • Author(s)
      北野雅之、工藤正俊
    • Total Pages
      773-776
    • Publisher
      医学書院

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Published: 2014-08-29  

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