2012 Fiscal Year Final Research Report
Investigation of ambulatory arterial stiffness index as a risk factor of cardiovascular disease
| Project/Area Number |
22590767
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Tohoku University |
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Principal Investigator |
KIKUYA Masahiro 東北大学, 東北メディカル・メガバンク機構, 准教授 (80361111)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 動脈硬化 / ABPM / 心血管病 / AASI / 血圧測定 |
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| Research Abstract |
Ambulatory arterial stiffness index (AASI) is an index of arterial stiffness and can be computed from ambulatory blood pressure (ABP) recordings. We found that (1) decrease in number of readings in ABP does not affect predictive accuracy of AASI for cardiovascular mortality, until the median number of readings per ABP recording is less than 35, (2) AASI computed by home blood pressure predicted cerebral infarction, (3) and had weak association with intima-media thickness of carotid artery.
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