Early detection of coronary artery disease using magnetocardiography

2012 Fiscal Year Final Research Report

• Project/Area Number: 22590769
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Circulatory organs internal medicine
• Research Institution: University of Tsukuba
• Principal Investigator: WATANABE Shigeyuki 筑波大学, 医学医療系, 教授 (90251058)
• Project Period (FY): 2010 – 2012
• Keywords: 心磁図 / 虚血性心疾患 / 傷害電流

Research Abstract

In this study, we performed magnetocardiographic study for early detection of the patients with coronary artery disease. Results: There were no electric current or only a weak current of leftward, inferior direction during ST interval in healthy subjects. However, in the patients with coronary stenosis exhibited 'abnormal current' during ST interval at rest, and this 'abnormal current' increased its magnitude after exercise. The directions of this 'abnormal current' coincided with the directions of the theoretical 'injury current'. We also succeeded to detect this abnormal current three-dimensionally. Moreover, we demonstrated this abnormal current will disappear about 10 days after coronary revascularization. We concluded magnetocardiography can detect the patients with coronary stenosis very sensitively.

Research Products

• [Journal Article] Subtraction Magnetocardiogram for Detecting Coronary (2010)
  • Author(s): Akihiko Kandori, Kuniomi Ogata, Tsuyoshi Miyashita, Hiroshi Takaki, Hideyuki Kanzaki, Syuji Hashimoto, Wataru Shimizu, Shiro Kamakura, Shigeyuki Watanabe, Kazutaka Aonuma
  • Journal Title: Ann Noninvasive Electrocardiol Volume: 15 Pages: 360-368
  • Peer Reviewed
• [Presentation] Magnetocardiographic findings of atrial depolarization and repolarization (2012)
  • Author(s): Yoshitsugu Nakagawa, Shigeyuki Watanabe, Masahiro Toyama, Yasuhisa Kuroda, Junya Honda, Hiroki Isono, Yukari Yoshida, Naoya Takeshi, Takeshi Inaba, Emi Arai, Yoko Sato, Akihiko Kandori
  • Organizer: 4th Asian Symposium on Magnetocardiography
  • Place of Presentation: Shanghai, China
  • Year and Date: 2012-08-23
• [Presentation] Magnetocardiographic detection of the injury current of the patients with ischemic heart disease (2012)
  • Author(s): Shigeyuki Watanabe, Masahiro Toyama, Yoshitsugu Nakagawa, Yukari Yoshida, Naoya Takeshi, Yasuhisa Kuroda, Junya Honda, Hiroki Isono,Takeshi Inaba, Emi Arai, Yoko Sato, Akihiko Kandori
  • Organizer: 4th Asian Symposium on Magnetocardiography
  • Place of Presentation: Shanghai, China
  • Year and Date: 2012-08-23
• [Presentation] 潜在的心筋虚血診断における心磁図の意義 (2012)
  • Author(s): 渡辺重行、吉田健太郎、佐藤陽子、青沼和隆、神鳥明彦、緒方邦臣
  • Organizer: 第27回日本生体磁気学会大会
  • Place of Presentation: 東京電機大学 千住キャンパス, 東京
  • Year and Date: 2012-05-31
• [Presentation] 心房細動に対するカテーテルアブレーション後の右心房磁場強度の上昇は、不整脈再発の予測因子である (2012)
  • Author(s): 吉田健太郎、佐藤陽子、緒方邦臣、神鳥明彦、渡辺重行、青沼和隆
  • Organizer: 第27回日本生体磁気学会大会
  • Place of Presentation: 東京電機大学 千住キャンパス, 東京
  • Year and Date: 2012-05-31
• [Presentation] Visualization of Normal and Abnormal Atrial or Ventricular Excitation Process using Magnetocardiography (2010)
  • Author(s): Shigeyuki Watanabe, Emi Arai, Yoko Sato, Yoshitsugu Nakagawa, Takeshi Inaba, Masahiro Toyama, Yasuhisa Kuroda, Toru Adachi, Akihiko Kandori, Akira Sato, Satoru Kawano, Kazutaka Aonuma
  • Organizer: The 3rd Asian Synposium on Magnetocardiography
  • Place of Presentation: Tsukuba, Japan
  • Year and Date: 2010-12-10
• [Presentation] Magnetocardiographical Visualization of Atrial Repolarization (Ta) Wave and its Response to Exercise (2010)
  • Author(s): Yoko Sato, Shigeyuki Watanabe, Emi Arai, Yoshitsugu Nakagawa, Takeshi Inaba, Masahiro Toyama, Yasuhisa Kuroda, Toru Adachi, Akihiko Kandori, Akira Sato, Satoru Kawano, Kazutaka Aonuma.
  • Organizer: The 3rd Asian Synposium on Magnetocardiography
  • Place of Presentation: Tsukuba, Japan
  • Year and Date: 2010-12-09