2012 Fiscal Year Final Research Report
Prediction of progression and efficacy of early treatment for asymptomatic pulmonary arterial hypertension
| Project/Area Number |
22590781
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Mie University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
ITO Masaaki 三重大学, 医学部附属病院, 教授 (00223181)
NAKAMURA Mashio 三重大学, 医学部附属病院, 講師 (40293774)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 臨床心血管病態学 / 肺高血圧症 / 運動負荷 / 薬物治療 / 早期介入 |
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| Research Abstract |
In the patients who have the risks of pulmonary arterial hypertension and positive response in right heart catheterization under exercise, mean pulmonary arterial pressure had not increased to the level of pulmonary hypertension during observational period. But the abnormal responses during exercise had improved in the pharmacological intervention group compared with no intervention group. Early pharmacological intervention might be effective for patients with borderline pulmonary arterial hypertension to prevent pulmonary vascular remodeling.
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