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2012 Fiscal Year Final Research Report

Development of software system for next-generation multi-channel high amplification and high resolution ECG and clinical application

Research Project

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Project/Area Number 22590792
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Circulatory organs internal medicine
Research InstitutionIwate Medical University

Principal Investigator

NAKAI Kenji  岩手医科大学, 歯学部, 教授 (90146035)

Project Period (FY) 2010 – 2012
Keywords心電図 / 致死的不整脈 / 再分極 / 心室細動 / Tp-e dispersion / 心室遅延電位 / 心房細動 / 遠隔医療
Research Abstract

We developed next -generation multi-channel high amplification and high resolution ECG. Our concept consisted
1. an analysis of repolarization phenomenon of myocardium (Tp-e dispersion, T-wave current alternans) for evaluating life -threatening arrhythmia
2. spectrum analysis for evaluating atrial fibrillation wave and substrate nature of ventricular late potential. We verified the clinical usefulness of n ext-generationmulti-functional solution ECG for clinical utility .
In addition, based on the experience of huge tsunami and earthquake of 3.11, we developed prototype high resolution multi-functional ECG for rem ote medical care or disaster.

  • Research Products

    (18 results)

All 2013 2012 2011 2010 2008 Other

All Journal Article (6 results) (of which Peer Reviewed: 5 results) Presentation (7 results) Book (2 results) Remarks (1 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Detection of peropartum myocardial burden by vector-projected 187 channel electrocardiography and serum NT-proBNP2013

    • Author(s)
      Terada M, Nakai K, Fukushima A, et al.
    • Journal Title

      Int Heart J

      Volume: 54 Pages: 140-145

  • [Journal Article] Interlead difference between T-peak to T-end intervals in resynchronization patients with an implantable cardioverter-defibrillator.2012

    • Author(s)
      Suzuki A, Shiga T, Nakai K, et al.
    • Journal Title

      Jelectrocardio

      Volume: 4 Pages: 706 -712

    • Peer Reviewed
  • [Journal Article] Body surface Two-dimensional spectral map of atrial fibrillation using vector-projected 187 channel electrocardiography2012

    • Author(s)
      Nakai K, Itoh M, Okabayashi H, et al.
    • Journal Title

      Int heart J

      Volume: 53 Pages: 5-10

    • Peer Reviewed
  • [Journal Article] Spatial distribution of ventricular late potentials assessed by the newly developed signal-averaged vector-projected 187-channel electrocardiogram in patients with old myocardial infarction.2012

    • Author(s)
      Futagawa K, Shoda M, Nakai K , Hiroshi Kasanuki H, Hagiwara N.
    • Journal Title

      J Arrhythmia

      Volume: 29 Pages: 28-33

    • Peer Reviewed
  • [Journal Article] Novel algorithm for identifying T-wave current density alternans using synthesized 187 -channel vector-projected body surface mapping.2011

    • Author(s)
      Nakai K, Takahashi S, Suzuki A, et al.
    • Journal Title

      Heart vessels

      Volume: 26 Pages: 160-167

    • Peer Reviewed
  • [Journal Article] Clinical Significance of Combined CYP2C9 and VKORC1 Genotypes in Japanese Patients Requiring Warfarin2011

    • Author(s)
      Miyagata Y, Nakai K, T Sugiyama.
    • Journal Title

      Int Heart J

      Volume: 52 Pages: 1-6

    • Peer Reviewed
  • [Presentation] Spectral Map of Atrial Fibrillation and Atrial flutter by a DREAM-ECG compared with 64 Channel Magnetocardiogram.2013

    • Author(s)
      Nakai K , Tsuboi J, Mitsunaga Y, Okabayashi H.
    • Organizer
      第77回日本循環器学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-16
  • [Presentation] New algorithm for a characterization of high -frequency signals and two-dimensional dominant frequency map by 187ch signal-averaged vector-projection ECG.2013

    • Author(s)
      Nakai K, Suzuki A, Shiga T, ほか
    • Organizer
      第77回日本循環器学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-15
  • [Presentation] DREAM-ECGによる心室脱分極・再分極二次元機能図の開発と心室細動例のリスク評価2012

    • Author(s)
      中居賢司、佐藤嘉洋、椚田房紀、ほか。
    • Organizer
      第27回日本不整脈学会
    • Place of Presentation
      千葉
    • Year and Date
      2012-10-12
  • [Presentation] Risk Stratification of Electrical Storm in Patients Receiving Cardiac Resynchronization Therapy With a Defibrillator by Signal-Averaged Synthesized 187ch Electrocardiography2012

    • Author(s)
      Nakai K, Suzuki A, Shiga T, et al.
    • Organizer
      5th APHRS
    • Place of Presentation
      Taipei
    • Year and Date
      2012-10-03
  • [Presentation] Risk Stratification of Ventricular Fibrillation by Two-dimensional Functional Image of Repolarization Dispersion and T-wave Alternance Using Synthesized 187-channel ECG2011

    • Author(s)
      Taipei
    • Organizer
      4th APHRS
    • Place of Presentation
      Fukuoka
    • Year and Date
      2011-09-22
  • [Presentation] Two-Dimensional Body Surface Dominant Frequency by Vector-Projected 187 -channel Electrocardiography May Evaluate a Characteristics of Atrial Fibrillation2011

    • Author(s)
      Nakai K, Itoh M, Tsuboi J, Mitsunaga Y, et al.
    • Organizer
      4th APHRS
    • Place of Presentation
      Fukuoka
    • Year and Date
      2011-09-22
  • [Presentation] Verification of Spacial Distribution of High-Frequency Potential of 187-ch Signal-Averaged Vector - Projected Electrocardiogram by 45-ch Body Surface Mapping and 64-ch Magnetocardiography.2011

    • Author(s)
      Nakai K, Itoh M, Komatsu T, et al.
    • Organizer
      第75回日本循環器学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-08-03
  • [Book] 心磁計および多チャンネル心電計、不整脈学(監修 井上 博、村川祐二)2012

    • Author(s)
      中居賢司
    • Total Pages
      206-211
    • Publisher
      南江堂
  • [Book] ベクトル合成187チャネル加算心電図による致死的不整脈の評価。不整脈ノンインベイシブ検査(監修 田邉晃久)、2010

    • Author(s)
      中居賢司
    • Total Pages
      252-263
    • Publisher
      医学書院
  • [Remarks]

    • URL

      http://www.iwate-med.ac.jp/education/gakubu_in/dent_kouza/sikanaika/

  • [Patent(Industrial Property Rights)] 心電図解析装置2012

    • Inventor(s)
      中居賢司、伊藤学、ほか2名
    • Industrial Property Rights Holder
      フクダ電子(株)、岩手医科大学、(株)アイシーエス
    • Industrial Property Number
      特願2006 -147362
    • Filing Date
      2012-11-30
  • [Patent(Industrial Property Rights)] 電流密度分布による心房細動波スペクトルとT波交互脈の二次元機能図解析アルゴリズムの発明2008

    • Inventor(s)
      中居賢司、伊藤学
    • Industrial Property Rights Holder
      岩手医科大学
    • Industrial Property Number
      特許2009P0241
    • Filing Date
      20081200

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Published: 2014-08-29  

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