2012 Fiscal Year Final Research Report
Vascular Biological Profile on Endothelial Progenitor Cell Origin and Differentiation
| Project/Area Number |
22590796
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Tokai University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
ASAHARA Takayuki 東海大学, 医学部, 教授 (20246200)
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| Research Collaborator |
SHIZUNO Tomoko 東海大学, 医学部, 研究技術員
ITO Rie 東海大学, 医学部, 研究技術員
ITOH Johbu 東海大学, 医学部, 研究技術員
ITOH Yoshiko 東海大学, 医学部, 研究技術員
KAMIGUCHI Hiroshi 東海大学, 医学部, 研究技術員
OKADA Yoshinori 東海大学, 医学部, 研究技術員
IIDA Yumi 東海大学, 医学部, 研究技術員
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| Project Period (FY) |
2010 – 2012
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| Keywords | 血管内皮前駆細胞 / 血管再生 / 分化 / 造血幹細胞 |
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| Research Abstract |
Circulating endothelial progenitor cell (EPC) is known to possess vascular repair/regeneration ability. However, the origin and differentiation cascade has yet to be elucidated. Our established analytical assay system of EPC expansion and differentiation revealed the functional features of EPC origin and differentiation. The findings provide us the potent information to develop diagnostic and therapeutic strategies for cardiovascular diseases.
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