2012 Fiscal Year Final Research Report

Regenerative medicine of COPD by Erythropoietin

Research Project

Project/Area Number	22590836
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Respiratory organ internal medicine
Research Institution	Gifu University
Principal Investigator	OHNO Yasushi 岐阜大学, 医学系研究科, 助教 (00334938)
Co-Investigator(Kenkyū-buntansha)	MINATOGUCHI Shinya 岐阜大学, 医学系研究科, 教授 (20190697)
Project Period (FY)	2010 – 2012
Keywords	COPD / エリスロポイエチン / 再生医学
Research Abstract	We made COPD model rabbit by elastase inhalation. As a result, the pulmonary emphysema-like change of the lungs of the human COPD resemblance. It enforced the Tetomilast dosage to provide PD4 inhibition having an antioxidant action as treatment orally. The progress to a pulmonary emphysema-like change was controlled by the evaluation four weeks later. In addition, the restraint of the aggravation of the restraint breathing function of the oxidation stress.