2012 Fiscal Year Final Research Report
The study on administration route of T-cell independent vaccinefrom the point view of bronchus-associated lymphoid tissue
| Project/Area Number |
22590855
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Hamamatsu University School of Medicine |
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Principal Investigator |
CHIDA Kingo 浜松医科大学, 医学部, 准教授 (40197611)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 気管支随伴リンパ組織 / T 細胞非依存不活化ワクチン / 肺炎球菌莢膜多糖体ワクチン / 経鼻投与 |
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| Research Abstract |
In order to enhance the efficacy of pneumococcal capsular polysaccharide vaccine (PPV), we compared the subcutaneous administration of PPV with intranasal route of PPV. Intranasal administration caused the induction of PPV -specific IgG antibody, but not subcutaneous vaccination.
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