2012 Fiscal Year Final Research Report
molecular signature for detection of intractable tumors
| Project/Area Number |
22590858
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
ARIMA Chinatsu 名古屋大学, 大学院・医学系研究科, 特任助教 (00534843)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 悪性胸膜中皮腫 / 肺癌 / プロテオミクス |
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| Research Abstract |
We employed shotgun proteomics together with peptide labeling technology to analyze comprehensive protein expression profiles of malignant pulmonary mesothelioma (MPM) and lung cancer and hundreds of candidate marker protein have been identified. Thus, our findings demonstrate that the combined proteomic technology is an efficient strategy for global proteomic analysis to discover novel biomarkers. We have applied two patents according to our observations.
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