2012 Fiscal Year Final Research Report
Evaluation of effects of ghrelin on patients with advanced lung cancer
| Project/Area Number |
22590867
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | University of Miyazaki |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YANAGI Shigehisa 宮崎大学, 医学部, 助教 (60404422)
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| Co-Investigator(Renkei-kenkyūsha) |
NAKAZATO Masamitsu 宮崎大学, 医学部, 教授 (10180267)
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| Project Period (FY) |
2010 – 2012
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| Keywords | グレリン / 肺癌 / カヘキシア |
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| Research Abstract |
The relation between plasma ghrelin levels and QOL scores in patients with advanced lung cancer who was received chemotherapy was evaluated. In patients with poor QOL scores after chemotherapy, plasma levels of ghrelin were significantly lowered compared with the those of patients with good QOL scores(poor QOL 17.0±7.9 fmol/ml vs good QOL 6.3±2.2 fmol/ml, p = 0.016).
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