2012 Fiscal Year Final Research Report
INVOLVMENT OF TH17 CELLS IN TUMOR ANGIOGENESIS INDUCED BY INTERACION BETWEEN NON-SMALL CELL LUNG CANCER CELLS AND INTERSTITIAL STROMAL CELLS
Project/Area Number |
22590869
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Respiratory organ internal medicine
|
Research Institution | Josai University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
HAGIWARA Kouiti (00240705)
|
Co-Investigator(Renkei-kenkyūsha) |
TAGAWA Masatoshi (20171572)
|
Project Period (FY) |
2010 – 2012
|
Keywords | サイトカイン / 肺癌 / Th17 細胞 / 血管新生 / 血管新生因子 |
Research Abstract |
Th17 cells were isolated and culture supernatants were collected. Culture supernatants of Th17 cells were found to have the activity to induce neovascular formation, and this activity was inhibited, in part, by an anti-IL-17 antibody.
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