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2012 Fiscal Year Final Research Report

The efficacy and role ofanti-lipid mediators on pulmonary fibrosis

Research Project

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Project/Area Number 22590871
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Respiratory organ internal medicine
Research InstitutionKeio University

Principal Investigator

FUKUNAGA Koichi  慶應義塾大学, 医学部, 講師 (60327517)

Co-Investigator(Kenkyū-buntansha) ASANO Koichiro  慶應義塾大学, 医学部, 准教授 (60192944)
Co-Investigator(Renkei-kenkyūsha) ARITA Makoto  東京大学, 大学院・薬学系研究科, 准教授 (80292952)
Project Period (FY) 2010 – 2012
Keywords肺線維症 / 抗炎症性脂質メディエーター
Research Abstract

Pulmonary fibrosis is a progressive disease of unknown etiology and poor prognosis because there is no effective therapy. In the current study, using an experimental murine model of pulmonary fibrosis, EPA derived resolving E1 (RvE1) and high dose of EPA

  • Research Products

    (2 results)

All 2012 2010

All Journal Article (2 results) (of which Peer Reviewed: 2 results)

  • [Journal Article] Resolvin E1 maintains macrophage function under cigarette smoke-induced oxidative stress.2012

    • Author(s)
      Takamiya R, Fukunaga K, Arita M et al.
    • Journal Title

      FEBS Open Bio

    • Peer Reviewed
  • [Journal Article] The anti-inflammatory and proresolving mediator resolvin E1 protects mice from bacterial pneumonia and acute lung injury.2010

    • Author(s)
      Fukunaga K, Seki H, Arita M, Levy BD et al.
    • Journal Title

      J Immunol.

      Volume: 184(2) Pages: 836-43

    • Peer Reviewed

URL: 

Published: 2014-08-29  

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