2012 Fiscal Year Final Research Report
Studying the CBF leukemogenesis and developing anti-cancer agents
| Project/Area Number |
22591026
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Hematology
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| Research Institution | Osaka University (2012)
The University of Tokyo (2010-2011) |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Keywords | 動物 / 癌 / 遺伝子 |
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| Research Abstract |
RUNX1 Dominant Inhibition has been proposed as a central dogma of CBF leukemogenesis. The project has clarified that RUNX1 is required for CBF leukememogenesis and RUNX1 and HATs maybe good therapeutic targets.
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