2012 Fiscal Year Final Research Report
Functional neuroimaging in children with anorexia nervosa
| Project/Area Number |
22591143
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Kurume University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
ISHIBASHI Masatoshi 久留米大学, 医学部, 教授 (20168256)
OKAMURA Hisayoshi 久留米大学, 高次脳疾患研究所, 助教 (00454918)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 思春期やせ症 / 近赤外線光トポグラフィー / 脳科学 / 摂食障害 / 神経性無食欲症 |
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| Research Abstract |
Anorexia nervosa (AN), which commonly occurs during adolescence in girls, is a disturbance of eating habits that is characterized by excessive preoccupation with body weight, shape, and food intake. The advanced neuroimaging studies showed that children with AN have remarkable concern with “attachment” which infants have experienced during their early childhood. It showed also significant decreased inhibitory neurogenic function in the cingulate cortex which control emotion, according to higher anxious and depressive symptoms. The abnormal neurogenic function returned to normal after bodyweight gained. Furthermore, eye-tracking examination revealed the evidence of preoccupation to food selectivity and shyness, which were difficult to be evaluated by patients. This study might contribute to patients and their parents for understanding well regarding AN
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[Journal Article] Prefrontal brain function in children with anorexia nervosa:A near-infrared spectroscopy study.2011
Author(s)
Nagamitsu S, Araki Y, Ioji T, Yamashita F, Ozono S, Kouno M, Iizuka C, Hara M, Shibuya I, Ohya T, Yamashita Y, Tsuda A, Kakuma T, Matsuishi T.
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Journal Title
BrainDev.
Volume: 33
Pages: 35-44
Peer Reviewed
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[Journal Article] Characteristic prefrontal blood volume patterns when imaging body type, high-calorie food, and mother-child attachment in childhood anorexia nervosa: A near infrared spectroscopy study.2010
Author(s)
Nagamitsu S, Yamashita F, Araki Y, Iizuka C, Ozono S, Komatsu H, Ohya T, Yamashita Y, Kakuma T, Tsuda A, Matsuishi T.
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Journal Title
BrainDev.
Volume: 32
Pages: 162-7
Peer Reviewed
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