2012 Fiscal Year Final Research Report
Basic Research on the establishment of the strategy for the treatment of neonatal hypoxic ischemic encephalopathy
| Project/Area Number |
22591198
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Embryonic/Neonatal medicine
|
|---|
| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 胎児医学 |
|---|
| Research Abstract |
To prevent periventricular leukomalacia (PVL), which is the major cause of the cerebral palsy in the preterm babies, we analyzed the effects of magnesium sulfate and hypothermia on the brain damage using in vivo/in vitro animal model. Magnesium sulfate significantly prevented the brain damage in vivo, and the hypothermia attenuated the apoptosis of the oligodendrocyte-precursor cells (OPC) through temporally preventing the proliferation of OPC.
|
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Journal Article] 左副腎摘出術を行い血圧コント ロール良好となったCushing症候群合併妊娠の一例2010
Author(s)
辻佳穂里,浦田陽子,小倉さやか,金高友妃子,山口俊一,小松篤,吉田志朗,兵藤博信,亀井良政,藤井知行,上妻志郎, 武谷雄二
-
Journal Title
日本産科婦人科学会東京地方部会会誌
Volume: 59
Pages: 358-361
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
