A research for restoration possibility of damaged brain function associated with eating disorders

2014 Fiscal Year Final Research Report

• Project/Area Number: 22591283
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Psychiatric science
• Research Institution: Nagoya University
• Principal Investigator: SATOSHI Tanaka 名古屋大学, 医学部附属病院, 助教 (00456675)
• Co-Investigator(Renkei-kenkyūsha): OZAKI Norio 名古屋大学, 大学院医学系研究科, 教授 (40281480) ; KIMURA Hiroyuki 名古屋大学, 医学部附属病院, 講師 (50378030) ; IIDAKA Tetsuya 名古屋大学, 大学院医学系研究科, 准教授 (70324366)
• Project Period (FY): 2010-04-01 – 2015-03-31
• Keywords: 摂食障害 / 神経性やせ症

Outline of Final Research Achievements

We have retrieved multi-modal data from eating disordered patients with malnutrition and controls, each around 40 samples. We found in patients 1)focal decrease of cerebral volume by MRI study, 2)signature temperament and character, and their correlations with depression, 3)characteristic cognition of thinness of self image, 4)signature cerebral functioning pattern by NIRS and its correlation to social insecurity, 5)build-up of stroop effect in Simon task and 6)relationship between nutrition therapy and liver dysfunction.
Some of these findings have been submitted to professional journals, and one have been published, others have been reported orally in academic conferences. We also have utilized these for improvement of therapeutic manual for eating disorder patients.

Free Research Field

精神医学