2012 Fiscal Year Final Research Report
Neuropathological studyof behavioral and psychological symptoms of dementia
| Project/Area Number |
22591292
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Yokohama City University |
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Principal Investigator |
TOGO Takashi 横浜市立大学, 医学研究科, 客員准教授 (20381501)
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| Co-Investigator(Renkei-kenkyūsha) |
ISEKI Eizo 順天堂大学, 医学部, 教授 (30203061)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 認知症 |
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| Research Abstract |
We investigated the pathological background of behavioral and psychological symptoms of dementia. In particular, we investigated localization of FUS in human brains.The dendritic localization of FUS and its increase in FTLD-TDP may have some implication for the pathophysiology of neurodegenerative diseases.
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[Journal Article] Progressive nonfluent aphasia: a rare clinical subtype of FTLD-TDP in Japan2012
Author(s)
Aoki N, Tsuchiya K, Kobayashi Z, Arai T, Togo T, Miyazaki H, Kondo H, Ishizu H, Uchikado H, Katsuse O, Hirayasu Y, Akiyama H
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Journal Title
Neuropathology
Volume: 32(3)
Pages: 272-9
DOI
Peer Reviewed
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[Journal Article] Neuropathological investigation of the hypometabolic regions on positron emission tomography with [18F] fluorodeoxyglucose in patients with dementia with Lewy bodies2012
Author(s)
Kasanuki K, Iseki E, Fujishiro H, Yamamoto R, Higashi S, Minegishi M, Togo T, Katsuse O, Uchikado H, Furukawa Y, Hino H, Kosaka K, Sato K, Arai H
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Journal Title
J Neurol Sci.
Volume: 314(1-2)
Pages: 111-9
DOI
Peer Reviewed
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[Journal Article] Localization of MAP1-LC3 in vulnerable neurons and Lewy bodies in brains of patients with dementia with Lewy bodies.2011
Author(s)
Higashi S, Moore DJ, Minegishi M, Kasanuki K, Fujishiro H, Kabuta T, Togo T, Katsuse O, Uchikado H, Furukawa Y, Hino H, Kosaka K, Sato K, Arai H, Wada K, Iseki E
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Journal Title
J Neuropathol Exp Neurol
Volume: 70(4)
Pages: 264-80
DOI
Peer Reviewed
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[Journal Article] Gray matter lesions in Nasu-Hakola disease: a report on three autopsy cases.2011
Author(s)
Aoki N, Tsuchiya K, Togo T, Kobayashi Z, Uchikado H, Katsuse O, Suzuki K, Fujishiro H, Arai T, Iseki E, Anno M, Kosaka K, AkiyamaH, Hirayasu Y
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Journal Title
Neuropathology
Volume: 31(2)
Pages: 135-43
DOI
Peer Reviewed
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[Journal Article] Distribution of cerebral amyloid deposition and its relevance to clinical phenotype in Lewy body dementia2010
Author(s)
Fujishiro H, Iseki E, Higashi S, Kasanuki K, Murayama N,Togo T, Katsuse O, Uchikado H, Aoki N, Kosaka K, Arai H, Sato K
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Journal Title
Neurosci Lett
Volume: 486(1)
Pages: 19-23
DOI
Peer Reviewed
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