2011 Fiscal Year Final Research Report
Boundary and heterogeneity of Pervasive Deve I opmenta I Di sorder Not Otherwise Specified研究代表者
| Project/Area Number |
22591311
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | National Center of Neurology and Psychiatry |
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Principal Investigator |
KAMIO Yoko 独立行政法人国立精神・神経医療研究センター, 精神保健研究所児童・思春期精神保健研究部, 部長 (00252445)
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| Co-Investigator(Renkei-kenkyūsha) |
NORIUCHI Madoka 独立行政法人国立精神・神経センター, 精神保健研究所児童・思春期精神保健研究部, 外来研究員 (20571897)
KIKUCHI Yoshiaki 首都大学東京, 人間健康科研究科, 教授 (50134739)
INADA Naoko 独立行政法人国立精神・神経センター, 精神保健研究所児童・思春期精神保健研究部, 外来研究員 (60466216)
TOBIMATSU Shozo 九州大学, 医学研究科, 教授 (40164008)
YAMAZAKI Takao 九州大学, 医学研究科, 特任助教 (70404069)
ROKUTAN Kazuhito 徳島大学, ヘルスバイオサイエンス研究部, 教授 (10230898)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 児童・思春期精神医学 / 広汎性発達障害 |
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| Research Abstract |
The aim of the current study was to determine whether the boundary between PDD-NOS and the other PDDs, or that between PDD-NOS and subthreshold PDD exists, For this purpose, we examined toddlers, children, and adults with PDD cross-sectionally or longitudinally on the behavioral, neurophysiological, and molecular level. As a result, we could not find evidence supporting the validity of PDD-NOS, instead autistic-specific behavioral, neurophysiological, and molecular features were found in individuals with PDD-NOS and subthreshold PDD. This indicates that the arbitrary boundary of PDD-NOS should be reconsidered
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