2012 Fiscal Year Final Research Report
Optimization of local cerebral cortical thickness measurement and comparison of cortical thickness and cortical volume data
| Project/Area Number |
22591316
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Radiation science
|
|---|
| Research Institution | Nihon University |
|---|
Principal Investigator |
ABE Osamu 日本大学, 医学部, 教授 (50302716)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
SHIZUKUISHI Takashi 日本大学, 医学部, 助手 (30570741)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 中枢神経 / 皮質厚 / 皮質容積 / ボクセルベース解析 |
|---|
| Research Abstract |
In this study, we extracted the regional cerebral cortical structural information from 3 dimensional T1-weighted magnetic resonance images using several segmentation algorithms. We compared cortical thickness data with cortical volumes and volumetric loss of brain tissue among the same subject groups in a voxel-wise manner. Although we observed significant regional structural changes in all the methods, spatial distribution with significant changes were different among algorithms, which suggested these methods have different types of information regarding brain structures.
|
Research Products
(14 results)
