Non-invasiveassessment ofaorticvalveand perivalvular apparatus with multislice computed tomography : a comparison with echocardiography.

2012 Fiscal Year Final Research Report

• Project/Area Number: 22591377
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Radiation science
• Research Institution: University of Occupational and Environmental Health, Japan
• Principal Investigator: TSUDA Yuki 産業医科大学, 医学部, 助教 (50525491)
• Co-Investigator(Kenkyū-buntansha): OTSUJI Yutaka 産業医科大学, 医学部, 教授 (30264427) ; OKAZAKI Masahiro 産業医科大学, 医学部, 准教授 (40233316)
• Project Period (FY): 2010 – 2012
• Keywords: 医用画像工学 / 循環器

Research Abstract

We compared multislice computed tomography(MSCT)analysis of aortic valve and perivalvular apparatus to echocardiography (UCG) noninvasively. In consecutive 400 patients, MSCT scan was performed for evaluation of coronary artery disease from April 2010 to March 2013. Of these, 389 patients had no aortic stenosis, and llpatients hadmoderate to severe aortic stenosis. Of these llAS patients,8patients had coronary artery stenosis (>50% stenosis), but 3 patients had no coronary artery stenosis. All AS patients had severe aortic valve calcification, and MSCT could detect all number of aortic valve leaflets in ll AS patients but UCG could recognize only 70f ll AS patients. The mean area of aortic valve by UCG was significantly snlaller than that obtained by MSCT (UCG:0.65cm^2 versus MSCT:0.77cm^2, p〈0.05). The mean diameter of aortic annulus by UCG was smaller than that of obtained by MSCT but not significant(UCG:22.1mm versus MSCT:23.9mm, P=0.45). The mean LV ejection fraction was 45%and was similar by UCG and by MSCT. Thereby, MSCT may be helpful for aortic valve replacement and/or for CABG.