• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2012 Fiscal Year Final Research Report

Development of Functional Image-Guided Radiotherapy Planning inIntensity-Modulated Radiation Therapy (IMRT) for Lung Cancer

Research Project

  • PDF
Project/Area Number 22591385
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionHiroshima University

Principal Investigator

KIMURA Tomoki  広島大学, 病院, 講師 (90379876)

Co-Investigator(Kenkyū-buntansha) NAGATA Yasushi  広島大学, 医歯薬保健学研究院, 教授 (10228033)
MURAKAMI Yuji  広島大学, 医歯薬保健学研究院, 講師 (10403528)
Project Period (FY) 2010 – 2012
Keywords放射線腫瘍学
Research Abstract

We performed a simulation study in eight lung cancer patients, and concluded functional image-guided radiotherapy planning based on low attenuation area (LAA) in IMRT or IMAT appeared to be effective in preserving a functional lung in lung cancer patients with chronic obstructive pulmonary disease (COPD). After that, Hiroshima University Hospital Review Board approved this study, and we collected data of 4D-CT, pulmonary perfusion image, pulmonary function of lung cancer patients who received radiotherapy to determine optimal functional imaging.

  • Research Products

    (28 results)

All 2013 2012 2011 2010 Other

All Journal Article (10 results) (of which Peer Reviewed: 10 results) Presentation (12 results) Book (6 results)

  • [Journal Article] Stereotactic body radiation therapy combined with transcatheter arterial chemoembolization for small hepatocellular carcinoma2013

    • Author(s)
      Yohji Honda, Tomoki Kimura, Hiroshi Aikata, Tomoki Kobayashi, Takayuki Fukuhara, Keiichi Masaki, Takashi Nakahara, Noriaki Naeshiro, Atsushi Ono, Daisuke Miyaki, Yuko Nagaoki, Tomokazu Kawaoka, Shintaro Takaki, Akira Hiramatsu, Masaki Ishikawa,Hideaki Kakizawa, Masahiro kenjo,Shoichi Takahashi, Kazuo Awai, Yasushi Nagata and Kazuaki Chayama
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: 28 Pages: 530-536

    • Peer Reviewed
  • [Journal Article] Multi-institutional comparison of treatment planning using stereotactic ablative body radiotherapy for hepatocellular carcinoma -- benchmark for a prospective multi-institutional study2013

    • Author(s)
      Takahisa Eriguchi, Atsuya Takeda, Yohei Oku, Satoshi Ishikura, Tomoki Kimura, Shuichi Ozawa, Takeo Nakashima, Yukinori Matsuo, Mitsuhiro Nakamura, Yasuo Matsumoto, Sadanori Yamazaki, Naoko Sanuki, Yoshinori Ito
    • Journal Title

      Radiation Oncology 2013

      Volume: 8 Pages: 113

    • Peer Reviewed
  • [Journal Article] Radiation Pneumonitis in Patients with Lung and Mediastinal Tumors: A retrospective study of risk factors focused on pulmonary emphysema.2012

    • Author(s)
      Tomoki Kimura, Taro Togami, Hitoshi Takashima, Yoshihiro Nishiyama, Motoomi Ohkawa, Yasushi Nagata
    • Journal Title

      British J. Radiol

      Volume: 85 Pages: 135-141

    • Peer Reviewed
  • [Journal Article] Functional Image-Guided Radiotherapy Planning in Respiratory-Gated Intensity-Modulated Radiation Therapy (IMRT) for Lung Cancer Patients with chronic obstructive pulmonary disease (COPD).2012

    • Author(s)
      Tomoki Kimura, Ikuno Nishibuchi, Yuji Murakami, Masahiro Kenjo, Yuko Kaneyasu, Yasushi Nagata
    • Journal Title

      Int.J. Radiat. Oncol. Biol. Phys

      Volume: 82 Pages: e663-e670

    • Peer Reviewed
  • [Journal Article] Long-term outcomes of intraluminal brachytherapy in combination with external beam radiotherapy for superficial esophageal cancer2012

    • Author(s)
      Yuji Murakami, Yasushi Nagata, Ikuno Nishibuchi, Tomoki Kimura, Masahiro Kenjo, Yuko Kaneyasu, Tomoyuki Okabe, Yasutoshi Hashimoto and Yukio Akagi
    • Journal Title

      Int.J. Clin. Oncol

      Volume: 17 Pages: 263-271

    • Peer Reviewed
  • [Journal Article] A pilot feasibility study of neoadjuvant chemoradiotherapy with S-1 in patients with locally advanced gastric cancer featuring adjacent tissue invasion or JGCA-bulky-N2 lymph node metastases2012

    • Author(s)
      Tatsushi Inoue, Shinichi Yachida, Hisashi Usuki, Tomoki Kimura, Masanobu Hagiike, Keiichi Okano, and Yasuyuki Suzuki.
    • Journal Title

      Annals ofSurgical Oncology

      Volume: 19 Pages: 2937-2945

    • Peer Reviewed
  • [Journal Article] Hepatic arterial infusion chemotherapy using 5-fluorouracil and systemic interferon-αfor advanced hepatocellular carcinoma in combination with or without three-dimensional conformal radiotherapy to venous tumor thrombosis in hepatic vein or inferior vena cava2012

    • Author(s)
      Eisuke Murakami, Hiroshi Aikata, Daisuke Miyaki, Yuko Nagaoki, Yoshio Katamura, Tomokazu Kawaika, Shintaro Takaki, Akira Hiramatsu, Koji Waki, Shoichi Takahashi, Tomoki Kimura, Masahiro Kenjo, Yasushi Nagata, Masaki Ishikawa, Hideaki Kakizawa, Kazuo Awai and Kazuaki Chayama
    • Journal Title

      Hepatology Research

      Volume: 42 Pages: 442-453

    • Peer Reviewed
  • [Journal Article] 第51回日本肺癌学会シンポジウム 4 肺癌に対する高精度放射線治療の現状「4 次元照射と呼吸同期照射」2012

    • Author(s)
      木村智樹、西渕いくの、村上祐司,権丈雅浩,兼安祐子,永田 靖
    • Journal Title

      肺癌学会誌

      Volume: 52(2) Pages: 174-181

    • Peer Reviewed
  • [Journal Article] COPD を有する肺癌における 肺機能画像を用いた IMRT の試み2011

    • Author(s)
      木村智樹、西淵いくの、村上祐司、権丈雅浩、 兼安祐子、永田 靖
    • Journal Title

      癌の臨床

      Volume: 57(3) Pages: 109-115

    • Peer Reviewed
  • [Journal Article] Dynamic Computed Tomography Appearance of Tumor Response after Stereotactic Body Radiation Therapy for hepatocellular Carcinoma -How should we evaluate treatment effects?

    • Author(s)
      Tomoki Kimura, Shigeo Takahashi,Masahiro Kenjo, Ikuno Nishibuchi,Ippei Takahashi, Yuki Takeuchi, Yoshiko DOI:, Yuko Kaneyasu, Yuji Murakami, Yoji Honda, Hiroshi Aikata, Kazuaki Chayama, Yasushi Nagata
    • Journal Title

      Hepatology Research

    • Peer Reviewed
  • [Presentation] Imaging findings of liver parenchyma after stereotactic body radiation therapy for hepatocellular carcinoma: Evaluation by gadoxetate disodium-enhanced hepatic MRI2012

    • Author(s)
      Nakamura Y, Kimura T, Higaki T, Kaichi Y, Tatsugami F, Date S, Awai K
    • Organizer
      98thScientific Assembly and Annual Meeting RSNA 2012
    • Place of Presentation
      (Chicago). USA
    • Year and Date
      20121125-30
  • [Presentation] The treatment results and dosimetric analysis of Stereotactic Body Radiation Therapy (SBRT) with Transarterial Chemoembolization (TACE) for Hepatocellular Carcinoma (HCC)2012

    • Author(s)
      Tomoki Kimura, Shigeo Takahashi, Ikuno Nishibuchi, Ippei Takahashi, Yuki Takeuchi, Yoshiko DOI:, Masahiro Kenjo, Yuko Kaneyasu, Yuji Murakami, Yasushi Nagata
    • Organizer
      Proceedings of the 54thannual ASTRO Meeting
    • Place of Presentation
      (Boston), USA
    • Year and Date
      20121028-31
  • [Presentation] Portal Vein and Bile Duct Toxicity Following Stereotactic Body Radiation Therapy (SBRT) for Hepatocellular Carcinoma (HCC)2012

    • Author(s)
      Shigeo Takahashi, Tomoki Kimura, Ikuno Nishibuchi, Ippei Takahashi, Yuki Takeuchi, Yoshiko DOI:, Masahiro Kenjo, Yuko Kaneyasu, Yuji Murakami, Yasushi Nagata
    • Organizer
      Proceedings of the 54thannual ASTRO Meeting
    • Place of Presentation
      (Boston), USA
    • Year and Date
      20121028-31
  • [Presentation] Treatment Results of Definitive Radiation Therapy for Elderly Patients with Esophageal Squamous Cell Carcinoma2012

    • Author(s)
      Yuji Murakami, Yasushi Nagata, Ippei Takahashi, Yoshiko, Masahiro Kenjo, Yuko Kaneyasu, Tomoki Kimura
    • Organizer
      Proceedings of the 54thannual ASTRO Meeting
    • Place of Presentation
      (Boston), USA
    • Year and Date
      20121028-31
  • [Presentation] The Frequency of Adverse Events by Radiation Therapy for Atomic Bomb Survivors with Cancer2012

    • Author(s)
      Yoshiko DOI:, Masahiro Kenjo, Ippei Takahashi, Yuki Takeuchi, Shigeo Takahashi, Ikuno Nishibuchi, Yuko Kaneyasu, Yuji Murakami, Tomoki Kimura, Yasushi Nagata
    • Organizer
      Proceedings of the 54thannual ASTRO Meeting
    • Place of Presentation
      (Boston), USA
    • Year and Date
      20121028-31
  • [Presentation] Dynamic CT Appearance of Tumor Response and Radiation Injury of the Liver after Stereotactic Body Radiation Therapy (SBRT) for Hepatocellular carcinoma (HCC)2011

    • Author(s)
      Tomoki Kimura, Ikuno Nishibuchi, Yuji Murakami, Masahiro Kenjo, Yuko Kaneyasu, Yasushi Nagata
    • Organizer
      Proceedings of the 53thannual ASTRO Meeting
    • Place of Presentation
      (Miami), USA
    • Year and Date
      20111002-06
  • [Presentation] Treatment Results of Chemoradiotherapy with a Dose of > =60 Gy and an Elective Nodal Irradiation for Stage I Esophageal Squamous Cell Carcinoma2011

    • Author(s)
      Yuji Murakami, Ikuno Nishibuchi, Tomoki Kimura, Masahiro Kenjo, Yuko Kaneyasu, Yasushi Nagata
    • Organizer
      Proceedings of the 53thannual ASTRO Meeting
    • Place of Presentation
      (Miami), USA
    • Year and Date
      20111002-06
  • [Presentation] The Dynamics of Histone Variant H2A.Z upon DNA Damage2011

    • Author(s)
      Ikuno Nishibuchi, Tashiro S, Shima H, Tomoki Kimura, Yuji Murakami, Masahiro Kenjo, Yuko Kaneyasu, Yasushi Nagata
    • Organizer
      Proceedings of the 53thannual ASTRO Meeting
    • Place of Presentation
      (Miami), USA
    • Year and Date
      20111002-06
  • [Presentation] Outcomes of chemoradiotherapy with a high irradiation dose using a 3D radiation treatment planning system for esophageal cancer2011

    • Author(s)
      Yuji Murakami, Yasushi Nagata, Ikuno Nishibuchi, Tomoki Kimura, Masahiro Kenjo, Yuko Kaneyasu
    • Organizer
      2011 ASCO Gastrointestinal cancers Symposium
    • Place of Presentation
      (San Francisco). USA
    • Year and Date
      20110120-22
  • [Presentation] Time-Adjusted Internal Target Volume (TTV) based on Four-Dimensional Computed Tomography (4D-CT) for Radiotherapy Planning of Lung Cancer2010

    • Author(s)
      Ikuno Nishibuchi, Tomoki Kimura, Takeo Nakashima, Yusuke Ochi, Yuji Murakami, Masahiro Kenjo, Yuko Kaneyasu, Yasushi Nagata
    • Organizer
      Proceedings of the 52thannual ASTRO Meeting
    • Place of Presentation
      (San Diego), USA
    • Year and Date
      20101031-1104
  • [Presentation] Functional Image-guided Radiotherapy Planning in Respiratory-gated Intensity Modulated Radiation Therapy (IMRT) for Lung Cancer Patients with Pulmonary Emphysema2010

    • Author(s)
      Tomoki Kimura, Ikuno Nishibuchi, Yuji Murakami, Masahiro Kenjo, Yuko Kaneyasu, Yasushi Nagata
    • Organizer
      Proceedings of the 52thannual ASTRO Meeting
    • Place of Presentation
      (San Diego), USA
    • Year and Date
      20101031-1104
  • [Presentation] Sequential Chemoradiotherapy with 24 Gy of Cranial Irradiation for Intracranial Germinoma diagnosed with MRI2010

    • Author(s)
      Masahiro Kenjo, Kazuhiko Sugiyama, Fumiyuki Yamasaki, Yuji Murakami, Tomoki Kimura, Ikuno Nishibuchi, Yuko Kaneyasu, Kaoru Kurisu, Yasushi Nagata
    • Organizer
      Proceedings of the 52thannual ASTRO Meeting
    • Place of Presentation
      (San Diego), USA
    • Year and Date
      20101031-1104
  • [Book] 「外耳道癌」臨床放射線腫瘍学2012

    • Author(s)
      日本放射線腫瘍学研究機構編
    • Total Pages
      228-231
    • Publisher
      南江堂
  • [Book] 「唾液腺腫瘍」放射線治療計画ガイドライン 20122012

    • Author(s)
      日本医学放射線学会編
    • Total Pages
      106-110
    • Publisher
      メディカル教育研究社
  • [Book] Natanasabapathi G2012

    • Author(s)
      Tomoki Kimura
    • Total Pages
      59-66
    • Publisher
      InTech
  • [Book] 癌・放射線治療 20102010

    • Author(s)
      木村智樹
    • Total Pages
      738-746
    • Publisher
      篠原出版
  • [Book] 癌・放射線治療別冊 20102010

    • Author(s)
      木村智樹
    • Total Pages
      40-41
    • Publisher
      篠原出版
  • [Book] 癌・放射線治療別冊 20102010

    • Author(s)
      永田 靖、木村智樹
    • Total Pages
      48-49
    • Publisher
      篠原出版

URL: 

Published: 2014-08-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi