2012 Fiscal Year Final Research Report
The development of a novel technique for a rapid diagnosis of nodal metastasis using nanocrystal beads labeled anti-cytokeratine antibody.
| Project/Area Number |
22591471
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Kanazawa Medical University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Keywords | センチネルリンパ節 / 微小転移 |
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| Research Abstract |
We investigated a novel technique for a rapid diagnosis of nodal metastasis to achieve the prevalence of the sentinel node mapping for early gastric cancer. We tried to visualize metastatic foci in lymph nodes with 3-dimentionnary using the Micro X-CT equipment after the rapid immunohistological whole-mount staining using nanocrystal beads labeled anti-cytokeratine antibody. Regrettably, we failed to obtain any good results because of difficulty in setting of Micro X-CT and finding the low signal/noise regimen of whole-mount immunostaining.
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