2012 Fiscal Year Final Research Report
Research and development of liver regeneration with autologous bone marrow cell transplantation against the limitation of major hepatectomy
Project/Area Number |
22591498
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Digestive surgery
|
Research Institution | Jichi Medical University (2012) Tohoku University (2010-2011) |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
HAYASHI Hiroki (30422124)
UNNO Michiaki (70282043)
|
Project Period (FY) |
2010 – 2012
|
Keywords | 骨髄幹細胞 / 肝再生 / 大量肝切除 |
Research Abstract |
We intraperitoneally-administered carbon tetrachloride (CCl4) tosevere immunodeficient mouse (NOG mouse) and created chronic liver injury modeland hepatic failure model. We transplanted bone marrow cells of GFP-positive NOG mice into tail vein, small numb
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[Journal Article] Potential Utility of NOG Mice with Ubiquitous eGFP Expression (NOG-EGFP) as a High Quality Cancer Sampling System2012
Author(s)
Shima K, Mizuma M, Hayashi H, Nakagawa K, Okada T, Sakata N, Omura N, Kitamura Y, Motoi F, Naito T, Rikiyama T, Katayose Y, Egawa S, Ishii N, Horii A, Unno M
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Journal Title
J Exp Clin Cancer Res.
Volume: 31(1)
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[Presentation] 蛍光 NOG マウスの異種移植モデルを用いた高純度癌細胞サンプリングシステム2013
Author(s)
嶋健太郎,水間正道, 林 洋毅, 中川 圭, 岡田恭穂, 坂田直昭, 大村範幸, 北村 洋, 吉田 寛, 元井冬彦, 力山敏樹, 片寄 友, 江川新一, 石井直人, 堀井 明 , 海野倫明
Organizer
第113回日本外科学会定期学術集会
Place of Presentation
福岡
Year and Date
20130500
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[Presentation] An attempt to establish a high quality sampling system of cancer cells using a xenograft model of NOG-EGFP mice.2011
Author(s)
嶋健太郎,水間正道, 大村範幸, 林 洋毅, 中川 圭, 岡田恭穂, 元井冬彦, 力山敏樹, 片寄 友, 江川新一, 石井直人, 堀井 明, 海野倫明
Organizer
第70回日本癌学会学術集会
Place of Presentation
名古屋
Year and Date
20111000