2012 Fiscal Year Final Research Report
Diagnosis of malignant pancreatic tumor by the expression of MPF
Project/Area Number |
22591529
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Digestive surgery
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Research Institution | Wakayama Medical University |
Principal Investigator |
TANI Masaji 和歌山県立医科大学, 医学部, 准教授 (60236677)
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Co-Investigator(Kenkyū-buntansha) |
YAMAUE Hiroki 和歌山県立医科大学, 医学部, 教授 (20191190)
KAWAI Manabu 和歌山県立医科大学, 医学部, 講師 (40398459)
HIRONO Seiko 和歌山県立医科大学, 医学部, 助教 (60468288)
MIYAZAWA Motoki 和歌山県立医科大学, 医学部, 学内助教 (90549734)
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Project Period (FY) |
2010 – 2012
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Keywords | 膵臓外科学 |
Research Abstract |
We performed immune-chemical staining for the pancreatic cancer tissues. All of invasive pancreatic cancer cells expressed mesothelin, and 7 of 9 IPMN-derived pancreatic cancer cells also expressed mesothelin. In addition, the front of IPMN-derived cancer was demonstrated that mesothelin expressed strongly by immune-chemical staining. However, there was no MPF-positive cells. We concluded that it is necessary to consider the mechanism of mesothelin.
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