2012 Fiscal Year Final Research Report
The Clinical Trial of Novel Biodegradable External Film Releasing Rapamycin for CABG
| Project/Area Number |
22591532
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Tohoku University |
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Principal Investigator |
ODA Katsuhiko 東北大学, 大学院・医学系研究科, 非常勤講師 (60323002)
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| Co-Investigator(Kenkyū-buntansha) |
KAWAMOTO Shunsuke 東北大学, 大学院・医学系研究科, 准教授 (20400244)
MOTOYOSHI Naotaka 東北大学, 病院, 講師 (40375093)
SAIKI Yoshikatsu 東北大学, 大学院・医学系研究科, 教授 (50372298)
TABAYASHI Koichi 東北大学, 大学院・医学系研究科, 教授 (90142942)
AKASAKA Junetsu 東北大学, 大学病院, 講師 (80343044)
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| Project Period (FY) |
2010 – 2012
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| Keywords | Drug-delivery system / 循環器 / 心臓外科 / 臨床 / 虚血性心疾患 |
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| Research Abstract |
To develop a novel technology to prevent saphenous vein grafts stenosis in CABG, the clinical trial of external application of rapamycin-eluting film at anastomotic sites was conducted. During the study period, total 21 patients had been enrolled in this study, and no graft occlusion and no adverse effect of this film was observed. With this clinical trial, the safety and feasibility of this new DDS system have been established.
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Research Products
(1 results)
