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2012 Fiscal Year Final Research Report

Analysis of Epithelial-mesenchymal transition mechanism in Non-small cell lung cancer

Research Project

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Project/Area Number 22591571
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionKyushu University

Principal Investigator

SHOUJI Fumihiro  九州大学, 医学研究院, 助教 (90444851)

Co-Investigator(Kenkyū-buntansha) MAEHARA Yoshihiko  九州大学, 医学研究院, 教授 (80165662)
岡本 龍郎  九州大学, 大学病院, 助教 (80568626)
TAKENOYAMA Mitsuhiro  九州大学, 医学研究院, 助教 (10309966)
Project Period (FY) 2010 – 2012
Keywords呼吸器外科学
Research Abstract

Twist was significantly correlated with both pathological T factor and pleural invasionin squamous cell lung carcinoma. Moreover mesenchymal markers such as activin, podoplanin and PAI-1 were significantly associated with pathological T factor. Especially, both activin and PAI-1 were related with pleural invasion. N-cadherin was significantly correlated with intratumoral lymphatic invasion.

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Published: 2014-08-29  

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