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2012 Fiscal Year Final Research Report

Cerebral aneurysm rupture risk estimation of with artery thickness.

Research Project

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Project/Area Number 22591599
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Cerebral neurosurgery
Research InstitutionWaseda University (2012)
Tokyo University of Technology (2010-2011)

Principal Investigator

YI Qian  早稲田大学, 理工総合研究所, 客員教授 (80389147)

Co-Investigator(Kenkyū-buntansha) UMEZU Mitsuo  早稲田大学, 理工学部, 教授 (90132927)
MURAYAMA Yuichi  慈恵医科大学, 脳神経学科, 教授 (00239550)
Project Period (FY) 2010 – 2012
Keywords脳動脈瘤 / 血流シミュレーション / 臨床データベース
Research Abstract

Anew approach using the technology of solid-liquid interaction model to estimate the risk of aneurysm rupture was performed under hemodynamic conditions. Flow energy loss in aneurysms was significantly different between ruptured-aneurysms and stable-aneurysms. The preliminary study found that greater energy loss occurred when flow passed through ruptured aneurysms, when compared to unruptured aneurysms. This new concept of energy loss may become a useful tool for the prediction of aneurysm rupture. These preliminary results indicated that EL may be a useful parameter for the quantitative estimation of the risks of rupture for aneurysms.

  • Research Products

    (20 results)

All 2013 2012 2011 2010 Other

All Journal Article (12 results) Presentation (8 results)

  • [Journal Article] The Influence of Elastic Upstream Artery Length on Fluid-Structure Interaction Modelling : A Comparative Study using Patient-Specific Cerebral Aneurysm2013

    • Author(s)
      C J Lee, Y Zhang, H Takao, Y Murayama, and Y Qian
    • Journal Title

      Medical Engineering & Physics

      Volume: (Accept)

  • [Journal Article] Analysis of Morphologic and Hemodynamic Parameters for Unruptured Posterior Communicating Artery Aneurysms with Oculomotor Nerve Palsy2013

    • Author(s)
      Ying Yu, Jinyu Xu, Xi Wu, Yongfa Wu, Che Jiang, Qinghai Huang, Yi Qian, Jianmin Liu
    • Journal Title

      Am J Neuroradiol

      Volume: (Accepted)

  • [Journal Article] A Comparison of Estimation Methods for CFD Outflow Boundary Conditions Using Patient-Specific Carotid Artery2013

    • Author(s)
      Chang-Joon Lee, Nahoko Uemiya, Shoichiro Ishihara, Yu Zhang, Yi Qian
    • Journal Title

      Journal of Engineering in Medicine

      Volume: (Accepted)

  • [Journal Article] A combination of genetic, molecular and haemodynamic risk factors contributes to the formation, enlargement and rupture of brain aneurysms2013

    • Author(s)
      S Francis, J Tu Y Qian, A Avolio
    • Journal Title

      Journal of Clinical Neuroscience

      Volume: (Accepted)

  • [Journal Article] Numerical analysis of blood flow distribution in 4-branch and 3-branch vascula r grafts2013

    • Author(s)
      C Konouraa, T Yagi, M Nakamura, K Iwasaki, Y Qian, S Okudaf, A Yoshitakeg, H Shimizu, R Yozu, M Umezu
    • Journal Title

      Journal of Artificial Organs

      Volume: (accepted)

  • [Journal Article] A comparison of the hemodynamic effects of flow diverters on wide-necked and narrow-necked cerebral aneurysms2012

    • Author(s)
      Yong-Fa Wua, Peng-Fei Yang, Jie Shen, Qing-Hai Huang, Xing Zhang, Yi Qian Jian-Min Liu
    • Journal Title

      Journal of Clinical Neuroscience

      Volume: 19(11) Pages: 1520-4

  • [Journal Article] Investigation Of Intracranial Aneurysm Hemodynamics Following Flow Diverter Stent Treatment2012

    • Author(s)
      Y Zhang, W Chong, Y Qian
    • Journal Title

      Medical Engineering & Physics

      Volume: (Accept)

  • [Journal Article] Mean Arterial Pressure Required for Intracranial Bypass Grafts : An Investigation with Computational Hemodynamic Models2012

    • Author(s)
      S F Sia, Y Qian, Y Zhang, M K Morgan
    • Journal Title

      Neurosurgery

      Volume: 71(4) Pages: 826-31

  • [Journal Article] Hemodynamic differences between unruptured and ruptured intracranial aneurysms during observation2012

    • Author(s)
      H Takao, Y Murayama, S Otsuka, Y Qian, et al
    • Journal Title

      Stroke

      Volume: 43 Pages: 1436-9

  • [Journal Article] Flow Resistance Analysis of Extracranial-To-Intracranial (EC-IC) Vein Bypass2012

    • Author(s)
      Y Zhang, S F Sia, M K Morgan, Y Qian
    • Journal Title

      J Biomech

      Volume: 45 Pages: 1400-5

  • [Journal Article] Proposition of an outflow boundary approach for carotid artery stenosis CFD simulation2012

    • Author(s)
      Zhang Y, Furusawa T, Sia S F, Umezu M, and Qian Y
    • Journal Title

      Computer Methods in Biomechanics and Biomedical Engineering

  • [Journal Article] Risk Analysis of Unruptured Aneurysms Using Computed Fluid Dynamics Technology : Preliminary Results2011

    • Author(s)
      Y. Qian, H. Takao, M. Umezu and Y. Murayama
    • Journal Title

      AJNR Am J Neuroradiol

      Volume: 32(10) Pages: 1948-55

  • [Presentation] CFD Reveals Hemodynamic Differences Between Unruptured And Ruptured Intracranial Aneurysms During Observation2012

    • Author(s)
      H Takao, Y Murayama, T Ishibashi, I Yuki, S Otsuka, T Suzuki, S Masuda, A Mohamed, Y Qian (I Sen), M Yamamoto, and T Abe
    • Organizer
      Stroke
    • Place of Presentation
      USA
    • Year and Date
      20120000
  • [Presentation] Hemodynamic Simulation for Surgical Treatment of Congenital Heart Disease2012

    • Author(s)
      Y Qian, J L Liu, and J F Liu
    • Organizer
      34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2012 (EMBC'12),
    • Place of Presentation
      USA
    • Year and Date
      20120000
  • [Presentation] Estimation of an outflow boundary approach for carotid artery stenosis CFD simulation2012

    • Author(s)
      Y Qian
    • Organizer
      ICS 2012
    • Place of Presentation
      Madison, USA
    • Year and Date
      20120000
  • [Presentation] The Critical Risk Analysis for Middle Cerebral Artery (MCA) Aneurysm by hemodynamic Characteristics2011

    • Author(s)
      Y Qian, W Chong, J M Liu, Y Murayama
    • Organizer
      WFINT 2011
    • Place of Presentation
      Cape Town, South Africa
    • Year and Date
      20111100
  • [Presentation] Hemodynamic Features of Cerebral Aneurysms that Influence to Rupture2011

    • Author(s)
      Y Qian
    • Organizer
      ESCTAIC 22nd Annual Meeting
    • Place of Presentation
      Erlangen, Germany
    • Year and Date
      20111000
  • [Presentation] An Approach of Computational Hemodynamics for Cardiovascular Flow Simulation2011

    • Author(s)
      J L Liu, Y Qian T. Miyakoshi K. Itatani, K. Miyaji , M. Umezu
    • Organizer
      Proceedings of ASME-JSME-KSME Joint Fluids Engineering Conference 2011 AJK2011-03057
    • Place of Presentation
      茨城
    • Year and Date
      20110000
  • [Presentation] Computational Hemodynamic Analysis for TCPC Pulsatile Simulation with Considering the Influence of Respiration2010

    • Author(s)
      J L Liu, Y Qian , Q Sun, J F Liu, K Itatai , K Miyaji , and M Umezu
    • Organizer
      Proceedings of the ASME 2010 Summer Bioengineering Conference (SBC2010)
    • Place of Presentation
      Grande Beach Resort, Naples Florida, USA
    • Year and Date
      20100600
  • [Presentation] Numerical Simulation and Hemodynamic Analysis of the Modified Blalock-Taussig Shunt

    • Author(s)
      J L Liu, J Sun, , JF Liu, and Y Qian
    • Organizer
      35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC'13)
    • Place of Presentation
      Osaka

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Published: 2014-08-29  

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