2012 Fiscal Year Final Research Report
evaluation of plaque vulnerability by plasma oxidized LDL
| Project/Area Number |
22591600
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Kawasaki Medical School |
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Principal Investigator |
UNO Masaaki 川崎医科大学, 医学部, 教授 (90232884)
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| Co-Investigator(Kenkyū-buntansha) |
MATSUBARA Shunji 川崎医科大学, 医学部, 准教授 (60294675)
MATSUZAKI Kazuhito 川崎医科大学, 医学部, 講師 (90363168)
TOI Hiroyuki 川崎医科大学, 医学部, 講師 (80551960)
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| Co-Investigator(Renkei-kenkyūsha) |
MATSUURA Eiji 岡山大学, 医歯(薬)学総合研究科, 教授 (20181688)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 頸動脈狭窄症 / 酸化 LDL / 頸動脈エコー |
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| Research Abstract |
The association between oxidized low-density lipoprotein (OxLDL) and vulnerability of carotid plaque is suspected but not established. We performed this study to determine whether plasma OxLDL is useful biomarker as a vulnerability of carotid plaque. Plasma OxLDL levels were determined in 49 CEA and 47 CAS patients. However, this studydemonstrated no association between plasma OxLDL and vulnerability of carotid plaque.
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