2012 Fiscal Year Final Research Report
Feed-back system based on cortical electrogram during deep brain stimulation in Parkinson disease.
| Project/Area Number |
22591624
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Kinki University |
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Principal Investigator |
NAKANO Naoki 近畿大学, 医学部, 講師 (60258027)
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| Co-Investigator(Kenkyū-buntansha) |
KATO Amami 近畿大学, 医学部, 教授 (00233776)
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| Project Period (FY) |
2010 – 2012
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| Keywords | Parkinson's disease / Electrocorticogram / Deep brain stimulation |
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| Research Abstract |
It disclosed significant increase in the power of 20Hz frequencyband in the primary motor cortex with high frequency (over 100Hz) of STN stimulation.This power increase became more prominent as the stimulation point moved from ventral portion to dorsal portion of STN, which also correlated with improvement of motor symptom of the patients. Our study suggested that 20-Hz oscillatory brain activity in primary motor cortex evoked by stimulation of subthalamic nucleus might become a objective index for optimization of stimulation parameter in STN DBS therapy.
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Research Products
(16 results)
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[Journal Article] 脳深部刺激手術用 in situイメージングプローブの開発2011
Author(s)
野田俊彦, Pan Yi-Li, 田川礼人, 小林琢磨, 笹川清隆, 徳田崇, 畠中由美子, 中野直樹, 加藤天美, 塩坂貞夫, 太田淳
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Journal Title
電学論E
Volume: 131
Pages: 427-428
Peer Reviewed
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