2012 Fiscal Year Final Research Report
Detection of the mechanism for bone formation and treatment in patients with ossification of the posterior longitudinal ligament
| Project/Area Number |
22591628
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | University of Toyama |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SEKI Syoji 富山大学, 大学院・医学薬学研究部(医学), 助教 (00432112)
HAMAZAKI Kei 富山大学, 大学院・医学薬学研究部(医学), 准教授 (50533494)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 後縦靭帯骨化 / 全脊椎 / 脂肪酸 / ミード酸 |
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| Research Abstract |
We investigated the three studies indicated below. 1)Ossification of the posterior longitudinal ligament in not only the cervical spine, but also other spinal regions: analysis using multidetector CT of the whole spine, 2)Serum fatty acid in patients with ossification of the posterior longitudinal ligament and the ligamentum flavum, 3)The effect of mead acid for the metabolism of intervertebral disc cells.Results:1)The incidence of bridge formation in the cervical spine was higher in other spinal regions （M group) than in the cervical spine （C group). More females had a high OS index of the whole spine. 2)There was no significant difference was found in the concentration of mead acid between the patient group and the control group. 3)This study is undergoing. Not fully evaluated yet.
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