2012 Fiscal Year Final Research Report
Studies on a non-invasive fluid volume measurement method for critically ill pediatric patients
| Project/Area Number |
22591700
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Hirosaki University |
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Principal Investigator |
ISHIHARA Hironori 弘前大学, 医学(系)研究科(研究院), 准教授 (50111224)
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| Co-Investigator(Kenkyū-buntansha) |
TSUBO Toshihito 弘前大学, 医学部附属病院, 准教授 (30133870)
OKAWA Hirobumi 弘前大学, 医学(系)研究科(研究院), 講師 (40322953)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 細胞外液量 / 小児 / 心臓前負荷 / ブドウ糖 / 体液管理 |
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| Research Abstract |
Initial distribution volume of glucose (IDVG) using a small amount of glucose (1g or 2g) was found to be greater in pediatric patients (body weight >8kg) compared with adult patients. IDVG in children had a linear correlation with cardiac output and circulating blood volume as observed in adults, indicating that this measurement method is useful for fluid management in pediatric patients. Both 3 min and 5 min post-injection plasma glucose levels are required to reliably predict IDVG derived by a one-compartment model.
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