2012 Fiscal Year Final Research Report
Effects of Inhalational anesthetic exposure during pregnancy on neurodegeneration of neonatal mice
| Project/Area Number |
22591709
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Kobe University |
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Principal Investigator |
UEKI Masaaki 神戸大学, 大学院・医学研究科, 医学研究員 (20213332)
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| Project Period (FY) |
2010 – 2012
|
| Keywords | 吸入麻酔薬 / 脳神経変性 / 妊娠 |
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| Research Abstract |
Exposure of 1% isoflurane on pregnant mice (embryonic day 17) had an influence on learning function, morphological synapse formation (synaptophysin staining) and BDNF mRNA on postnatal day 7. Furthermore, environmental enrichment improved learning function.
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Research Products
(4 results)
