2012 Fiscal Year Final Research Report
Let's treat preterm labor with Proteoglycan !
| Project/Area Number |
22591813
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Hirosaki University |
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Principal Investigator |
TANAKA Kanji 弘前大学, 医学部附属病院, 准教授 (20311540)
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| Co-Investigator(Kenkyū-buntansha) |
FUKUYAMA Asami 弘前大学, 医学部附属病院, 助教 (30536511)
KAKIZAKI Ikuko 弘前大学, 医学(系)研究科, 准教授 (80302024)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 切迫早産 / プロテオグリカン / プロゲステロン / ヒト子宮頸管由来培養線維芽細胞 / 炎症性サイトカイン |
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| Research Abstract |
This study showed that both PG and P have an inhibitory effect on LPS-induced inflammation. This anti-inflammatory effect of PG and P was augmented by co-administration of both, suggesting for the first time that PG has an anti-inflammatory effect on human uterine cervical fibroblasts.
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