2012 Fiscal Year Final Research Report
A basic study on the effects of fetal circulation have on the placenta oxygenation dynamics by near-infrared spectroscopy
| Project/Area Number |
22591820
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Hamamatsu University School of Medicine |
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Principal Investigator |
SUZUKI Kazunao 浜松医科大学, 医学部附属病院, 講師 (50456571)
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| Co-Investigator(Kenkyū-buntansha) |
KANAYAMA Naohiro 浜松医科大学, 医学部, 教授 (70204550)
ITOH Hiroaki 浜松医科大学, 医学部附属病院, 准教授 (70263085)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 産科学 |
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| Research Abstract |
We recently found a significant elevation in placental tissue oxygen index (TOI) values in cases of fetal growth restriction using near-infrared spectroscopy (NIRS), indicating high oxygenation in the placental tissue. We hypothesized that insufficient fetoumbilical blood flow is causatively associated with high oxygenation levels in placental tissue. We transiently (for 15 sec) ligated the whole umbilicus, umbilical arteries, or veins of pregnant Clawn miniature pigs (102-113 days of gestation) and assessed the changes in TOI values of the placenta and fetus. The ligation significantly increased placental TOI values (p
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[Journal Article] Association Between Body Weight at Weaning and Remodeling in the Subcutaneous Adipose Tissue of Obese Adult Mice With Undernourishment In Utero.2013
Author(s)
Kohmura YK, Kanayama N, Muramatsu K, Tamura N, Yaguchi C, Uchida T, Suzuki K, Sugihara K, Aoe S, Sasaki T, Suganami T, Ogawa Y, Itoh H.
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Journal Title
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[Journal Article] Transient ligation of umbilical vessels elevates placental tissue oxygen index (TOI) values measured by near-infrared spectroscopy (NIRS) in clawn miniature pig animal model.2012
Author(s)
Suzuki K, Itoh H, Muramatsu K, Yamazaki K, Nagahashi K, Furuta N, Tamura N, Uchida T, Sugihara K, Sumimoto K, Kanayama N
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Journal Title
Clin Exp Obstet Gynecol
Volume: 39(3)
Pages: 293-8
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[Journal Article] Immunohistochemical detection of meconium in the fetal membrane2012
Author(s)
Furuta N, Yaguchi C, Itoh H, Morishima Y, Tamura N, Kato M, Uchida T, Suzuki K, Sugihara K, Kawabata Y, Suzuki N, Sasaki T, Horiuchi K, Kanayama N
Volume
33(1)
Pages
24-30
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[Journal Article] 母獣低換気による高二酸化炭素血症は臍帯血流遮断時の胎仔に保護的に作用する 近赤外線分光法を用いた動物実験による検討2012
Author(s)
鈴木 一有, 下山 華, 村松 慧子, 山崎 香織, 長橋 ことみ, 幸村 友季子, 柴田 俊章, 内田 季之, 杉原 一廣, 伊東 宏晃, 住本 和博, 金山 尚裕
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Journal Title
日本産科婦人科学会雑誌(0300-9165)
Volume: 64巻 2号
Pages: 564
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