2012 Fiscal Year Final Research Report
Clinical usefulness of human papillomavirus testing
| Project/Area Number |
22591846
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
YOSHIKAWA Hiroyuki 筑波大学, 医学医療系, 教授 (40158415)
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| Project Period (FY) |
2010 – 2012
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| Keywords | ヒトパピローマウイルス / 子宮頸癌 |
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| Research Abstract |
Infections by oncogenic human papillomaviruses (HPVs) are a major risk factor of cervical cancer. To evaluate the clinical usefulness of HPV DNA testing and serology, we analyzed follow-up data of 570 women with low-grade cervical lesions. Our findings suggested that HPV genotyping and antibody assays for women with low-grade cervical abnormalities may be useful for identifying populations at increased or decreased risk of disease progression.
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Research Products
(7 results)
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[Journal Article] Do neutralizing antibody responses generated by human papillomavirus infections favor a better outcome of low-grade cervical lesions?2012
Author(s)
Ochi H, Matsumoto K, Kondo K, Oki A, Furuta R, Hirai Y, Ya sug i T, TakatsukaN, Maeda H, Mitsuhashi A, Fujii T, Kawana K, Iwasaka T, Yaegashi N, Watanabe Y, Nagai Y, Kitagawa T, Kanda T, Yoshikawa H for Japan HPV And Cervical Cancer (JHACC) Study Group
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Journal Title
J Med Virol
Volume: 84
Pages: 1128-34
DOI
Peer Reviewed
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[Journal Article] Predicting the Progression of Cervical Precursor Lesions by Human Papillomavirus Genotyping: A Prospective Cohort Study2011
Author(s)
Matsumoto K, Oki A, Furuta R, Maeda H, Yasugi T, Takatsuka N, Hirai Y, Mitsuhashi A, Fujii T, Iwasaka T, Yaegashi N, Watanabe Y, Nagai Y, Kitagawa T, Yoshikawa H
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Journal Title
Int J Cancer
Volume: 128
Pages: 2898-2910
DOI
Peer Reviewed
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