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2012 Fiscal Year Final Research Report

Clinical usefulness of human papillomavirus testing

Research Project

  • PDF
Project/Area Number 22591846
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Obstetrics and gynecology
Research InstitutionUniversity of Tsukuba

Principal Investigator

MATSUMOTO Koji  筑波大学, 医学医療系, 准教授 (30302714)

Co-Investigator(Renkei-kenkyūsha) YOSHIKAWA Hiroyuki  筑波大学, 医学医療系, 教授 (40158415)
Project Period (FY) 2010 – 2012
Keywordsヒトパピローマウイルス / 子宮頸癌
Research Abstract

Infections by oncogenic human papillomaviruses (HPVs) are a major risk factor of cervical cancer. To evaluate the clinical usefulness of HPV DNA testing and serology, we analyzed follow-up data of 570 women with low-grade cervical lesions. Our findings suggested that HPV genotyping and antibody assays for women with low-grade cervical abnormalities may be useful for identifying populations at increased or decreased risk of disease progression.

  • Research Products

    (7 results)

All 2013 2012 2011

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (4 results)

  • [Journal Article] Human Papillomavirus Infection and Risk for Cervical Cancer in Japan2013

    • Author(s)
      Matsumoto K, Yoshikawa H.
    • Journal Title

      J Obstet Gynecol

      Volume: 39 Pages: 7-17

    • DOI

      doi:10.1111/j.1447-0756.2012.01977.x

    • Peer Reviewed
  • [Journal Article] Do neutralizing antibody responses generated by human papillomavirus infections favor a better outcome of low-grade cervical lesions?2012

    • Author(s)
      Ochi H, Matsumoto K, Kondo K, Oki A, Furuta R, Hirai Y, Ya sug i T, TakatsukaN, Maeda H, Mitsuhashi A, Fujii T, Kawana K, Iwasaka T, Yaegashi N, Watanabe Y, Nagai Y, Kitagawa T, Kanda T, Yoshikawa H for Japan HPV And Cervical Cancer (JHACC) Study Group
    • Journal Title

      J Med Virol

      Volume: 84 Pages: 1128-34

    • DOI

      doi:10.1002/jmv.23258

    • Peer Reviewed
  • [Journal Article] Predicting the Progression of Cervical Precursor Lesions by Human Papillomavirus Genotyping: A Prospective Cohort Study2011

    • Author(s)
      Matsumoto K, Oki A, Furuta R, Maeda H, Yasugi T, Takatsuka N, Hirai Y, Mitsuhashi A, Fujii T, Iwasaka T, Yaegashi N, Watanabe Y, Nagai Y, Kitagawa T, Yoshikawa H
    • Journal Title

      Int J Cancer

      Volume: 128 Pages: 2898-2910

    • DOI

      doi:10.1002/ijc.25630

    • Peer Reviewed
  • [Presentation] 要望講演 中央病理診断に基づく臨床研究:子宮頸部「LSIL/CIN1-2患者の多施設共同コホート研 究 」2012

    • Author(s)
      松本光司、吉川裕之
    • Organizer
      第51回日本臨床細胞学会秋期大会
    • Place of Presentation
      朱鷺メッセ、新潟
    • Year and Date
      2012-11-09
  • [Presentation] LSIL・HSILトリアージのためのHPVタイピング検査の有用性2012

    • Author(s)
      松本光司、中村優子、島袋剛二、西出健、永井公洋、佐藤豊実、沖明典、吉川裕之
    • Organizer
      第64回日本産科婦人科学術講演会
    • Place of Presentation
      神戸ポートピアホテル、神戸
    • Year and Date
      2012-04-14
  • [Presentation] ヒトパピローマウイルスのタイプとCIN3への進展リスク2011

    • Author(s)
      松本光司、沖明典、八杉利治、平井康夫、古田玲子、三橋暁、藤井多久磨、岩坂剛、八重樫伸生、渡部洋、長井裕、吉川裕之
    • Organizer
      第63回日本産科婦人科学会学術講演会
    • Place of Presentation
      リーガロイヤルホテル大阪、大阪
    • Year and Date
      2011-08-29
  • [Presentation] HPV16に対する血清中和抗体と子宮頚部前癌病変の消失・進展2011

    • Author(s)
      越智寛幸、松本光司、近藤一成、古田玲子、平井康夫、八杉利治、沖明典、吉川裕之
    • Organizer
      第63回日本産科婦人科学会学術講演会
    • Place of Presentation
      リーガロイヤルホテル大阪、大阪
    • Year and Date
      2011-08-29

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Published: 2014-08-29  

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