2012 Fiscal Year Final Research Report
Basic research on the origin of ocular vestibular evoked myogenicpotentials
| Project/Area Number |
22591875
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Keywords | 耳科学 |
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| Research Abstract |
To clarify the origin of ocular vestibular evoked myogenic potential (oVEMP), we performed experiments trying to record oVEMPs from guinea pigs. By inserting an electrode through lower eyelids and contacting it near extraocular muscles, we could record negative potentials with the peak latency of 3 msec. The potential was reduced by destruction of inner ear of the contralateral side, and was abolished by destruction of inner ears of both sides, suggesting that the response was dependent on the inner ears of both sides. Furthermore, by recoding directly from extraocular muscles, we confirmed that the oVEMPs in guinea pigs are originated from both the inferior oblique muscles and the inferior rectus muscles.
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