2012 Fiscal Year Final Research Report
Compensation for swallowing function due to the impairment of the laryngeal elevator muscles
| Project/Area Number |
22591913
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
BANBA Hitoshi 京都府立医科大学, 医学(系)研究科(研究院), 客員講師 (30360035)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 耳鼻咽喉科学 / 咽頭科学 / 嚥下 |
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| Research Abstract |
Laryngeal elevation surgery could be performed for patients with swallowing impairment responsible for reduced laryngeal elevation during swallowing. However, it is still uncertain whether this procedure would become a reasonable treatment for each patient. We therefore have investigated the neuronal mechanism that regulates the laryngeal elevator muscles and the alteration of the neural network due to partially deterioration of the laryngeal elevator muscles using mice. We have tried to reveal the effectiveness of the laryngeal elevation surgery for patients with injured laryngeal elevator muscles in in vivo mouse model.
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