2012 Fiscal Year Final Research Report
Gene Therapy for Head and Neck Cancer using Adeno-Associated Virus Vector Harboring Galanin Receptor type1
| Project/Area Number |
22591916
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Jichi Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
金澤 丈治 自治医科大学, 医学部, 准教授 (20336374)
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| Co-Investigator(Renkei-kenkyūsha) |
水上 浩明 自治医科大学, 医学部, 准教授 (20311938)
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| Project Period (FY) |
2010 – 2012
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| Keywords | AAV / GALR1 / 癌抑制遺伝子 / 遺伝子治療 / 頭頸部癌 |
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| Research Abstract |
The invention of new therapeutic approaches against HNSCC were eagerly anticipated. In this study, we first transduced Head and Neck Cancer cell lines using a recombinant adeno-associated virus serotype 2 (rAAV2)-GFP vector and confirmed a high GFP expres
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