2012 Fiscal Year Final Research Report
Preventive measure development for complications from Therapeutic Hypothermia.
| Project/Area Number |
22592017
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Emergency medicine
|
|---|
| Research Institution | Ehime University |
|---|
Principal Investigator |
AIBIKI Mayuki 愛媛大学, 大学院・医学系研究科, 教授 (70148162)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 低体温療法 / 心停止後症候群 / 頭部外傷 / 好中球機能 / 肺合併症 |
|---|
| Research Abstract |
We have found a tendency of lowering pulmonary involvements in patients undergoing hypothermia treated with daily dexamethasone (DX) administration of 5 mg for 7 days as compared to those in historical controls undergoing normothermia without DX treatment. ThisDX effect may be mediated through neutrophil depressions, which was revealed by experiments of evaluating the effects of DX on human neutrophils in vitro and in vivo.
|
