2012 Fiscal Year Final Research Report
Identification of emesis-inducing medullary neurons and anslysis of their functions.
| Project/Area Number |
22592057
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Functional basic dentistry
|
|---|
| Research Institution | Hokkaido University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
HIRAI Yoshiyuki 北海道大学, 大学院・歯学研究科, 助教 (40344519)
MAEZAWA Hitoshi 北海道大学, 大学院・歯学研究科, 教授 (80567727)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 口腔生理学 |
|---|
| Research Abstract |
We investigated how neurons in the area postrema known as a chemoreceptor trigger zone are related to the induction of nausea and/or emesis and to the control of food intake. We found that the neurons expressing H channels are closely related to the induction of nausea but they do not respond to amylin that is known as a satiety peptide. Responses to amylin were found only in the neurons not expressing H channels. We concluded that these date suggested the presence of functional differentiation between the neurons expressing H channels and the neurons not expressing H channels.
|
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] ZD7288の味覚嫌悪学習への影響2010
Author(s)
新保圭亮,平井喜幸,前澤仁志,石尾知亮,福田武志,戸塚靖則,舩橋誠
Organizer
第52回歯科基礎医学会,Journal of OralBiosciences,52(supple)
Place of Presentation
タワーホール船堀(東京)
Year and Date
2010-09-21
-
