2014 Fiscal Year Final Research Report
The establishment of guidelines for diagnosis and treatment of xerostomia
| Project/Area Number |
22592096
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Kyushu Dental College |
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Principal Investigator |
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| Project Period (FY) |
2010-04-01 – 2015-03-31
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| Keywords | 口腔乾燥症 / 唾液 / MRI / 診断 / 治療 |
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| Outline of Final Research Achievements |
We developed and clinically applied dynamic MR sialography as a new noninvasive diagnostic technique for the functional evaluation of salivary glands. We showed that dynamic MR sialographic images and data have a high potential as a diagnostic tool for Sjogren syndrome and xerostomia. In addition, we demonstrated that the high correlations were found between the changing ratio of the dynamic MR sialographic data, and improvement on clinical manifestations for dry mouth sensation after saline solution irrigation of the parotid glands and improvement of salivary flow rate in our study. We speculate that MR sialography could also predict the effectiveness of treatments for xerostomia other than the saline solution irrigation treatment.
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| Free Research Field |
歯科放射線学
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