2012 Fiscal Year Final Research Report
Dental cements containing sericin powder with cell biological properties show effect of wound healing
| Project/Area Number |
22592186
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Nagasaki University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TAIRA Yohsuke 長崎大学, 医歯薬学総合研究科, 准教授 (40226725)
HOTOKEZAKA Hitoshi 長崎大学, 医歯薬学総合研究科, 講師 (90199513)
KAMADA Kohji 長崎大学, 医歯薬学総合研究科, 助教 (60264256)
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| Project Period (FY) |
2010 – 2012
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| Keywords | セリシン / 生体材料学 / レジンセメント / コンポジットレジン / ヌープ硬さ / 創傷治癒 |
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| Research Abstract |
Sericin powder was added in a commercially available self-adhesive resin cement or resin-modified glass ionomer cement with various concentrations. Specimens were measured Knoop hardness from directly after specimen preparation to long-term immersion in distilled water. As a result, it was revealed that the hardening properties were equal to additive-free control when it was added 5.0% by weight in both resin cements.In addition, after crown preparation of the rat maxillary central incisor, temporary crownswere sealed with commercially available resin-modified glass ionomer cement containing sericin 5.0% by weight. As a result, the recovery of inflammation of a cornification epithelium and the attached gingiva seated the temporary crown with sericin-containing resin-modified glass ionomer cement was equivalent to healthy gingival control group after 3-months provisional cementation. The wound healing effect was not shown enough.
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