2012 Fiscal Year Final Research Report
Analysis of pathological and/or unphysiological root resorption mechanism focused on the two types of osteoclasts
| Project/Area Number |
22592274
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
DOMON Takanori 北海道大学, 大学院・歯学研究科, 教授 (50217618)
KIKUIRI Takashi 北海道大学, 大学院・歯学研究科, 助教 (10322819)
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| Co-Investigator(Renkei-kenkyūsha) |
DEYAMA Yoshiaki 北海道大学, 大学院・歯学研究科, 准教授 (80271667)
HASEGAWA Tomokazu 徳島大学, 大学病院, 講師 (50274668)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 破骨細胞 |
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| Research Abstract |
In this study, we examined the pathological and/or unphysiologicalroot resorption mechanism focused on the two types of osteoclasts. Our results weresuggested that morphologic characteristics of the osteoclasts varied according to thedown-regulation of Treg activity, difference of the major histocompatibility complex(MHC) haplotype, tensile force in culture condition and ROS scavengers.
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