Identification of ventilation obstructionsite of OSAS of children by the fluid simulation and construction of the treatment predictive model

2012 Fiscal Year Final Research Report

• Project/Area Number: 22592292
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Orthodontic/Pediatric dentistry
• Research Institution: Kagoshima University
• Principal Investigator: IWASAKI Tomonori 鹿児島大学, 医学部・歯学部附属病院, 講師 (10264433)
• Co-Investigator(Kenkyū-buntansha): YAMASAKI Youichi 鹿児島大学, 医歯学総合研究科, 教授 (30200645) ; HAYASAKI Haruaki 新潟大学, 医歯学総合研究科, 教授 (60238095) ; SAITOH Issei 新潟大学, 医歯学総合研究科, 准教授 (90404540)
• Project Period (FY): 2010 – 2012
• Keywords: 小児 OSAS / 上気道流体シミュレーション / 上顎骨急速拡大 / 鼻腔通気状態 / 舌位 / 咽頭気道体積

Research Abstract

The fluid mechinical simulation (FMS) was shown to be effectiveto detect a site of the upper airway obstruction. When we planned OSAS treatment, we proved efficacy of the combination of FMS and CBCT to diagnose the obstruction of the upper airway. And we evaluated the effect to nasal cavity ventilation, tongue posture, the pharynx airway volume of the maxillary rapid expansion (RME). RME enlarged pharynx airway with or without the improvement of the nasal cavity aeration state. This effectis effective for OSAS of children. We consider that the above-mentioned results help the construction of the future treatment predictive model.

Research Products

• [Journal Article] Tongue posture improvement and pharyngeal airway enlargement as secondary effects of rapid maxillary expansion: A cone-beam computed tomography study (2013)
  • Author(s): Iwasaki T, Saitoh I, Takemoto Y, Inada E, Kakuno E, Kanomi R, Hayasaki H, Yamasaki Y
  • Journal Title: American Journal of Orthodontics and Dentofacial Orthopedics Volume: Vol.143 Pages: 235-245
• [Journal Article] aluation of improvement of nasal airway ventilation following rapid maxillary expansion using computational fluid dynamics (2012)
  • Author(s): Iwasaki T, Saitoh I, Takemoto Y, Inada E, Kanomi R, Hayasaki H, Yamasaki Y
  • Journal Title: American Journal of Orthodontics and Dentofacial Orthopedics Volume: Vol.141, No.3 Pages: 269-278
• [Journal Article] Evaluation of upper airway obstruction in Class II children using fluid-mechanical simulation (2011)
  • Author(s): Iwasaki T, Saitoh I, Takemoto Y, Inada E, Kanomi R, Hayasaki H, Yamasaki Y
  • Journal Title: Am J Orthod Dentofacial Orthop Volume: Vol.139, No.2 Pages: e135-e145
• [Presentation] Analysis of upper airway obstruction in Class II children using fluid-mechanical simulation, the 8th Biennial Conference of the Pediatric Dentistry Association of Asia (PDAA) (2012)
  • Author(s): Yamasaki Y, Iwasaki T, Saitoh I, Takemoto Y, Inada E, Kakuno E, Kanomi R, Hayasaki H
  • Organizer: The 5 finalists of Scientific competition in Research Poster Session.
  • Place of Presentation: Sanur Paradisw Plaza Hotel, Bali in Indonesia
  • Year and Date: 20120524-26
• [Presentation] Detection of specific obstruction sites using fluid-structure interaction analysis in children with upper airway obstruction (2012)
  • Author(s): Iwasaki T, Saitoh I, Harada M, Miyashita K, Matsune S, Takemoto Y, Fukami A, Sato H, Inada E, Hasegawa H, Kakuno E, Kanomi R, Hayasaki H, Kurono Y, Yamasaki Y
  • Organizer: THE 7TH ASIAN SLEEP RESEAR SOCIETY CONGRESS
  • Place of Presentation: Taipei
  • Year and Date: 2012-11-30
• [Presentation] CBCTを用いた上顎骨側方急速拡大による舌位改善と咽頭気道拡大の評価 (2012)
  • Author(s): 岩崎智憲,嘉ノ海龍三,武元嘉彦,齊藤一誠,覚野恵梨子,早崎治明,山崎要一
  • Organizer: 第71回日本矯正歯科学会
  • Place of Presentation: 盛岡市
  • Year and Date: 2012-09-28
• [Presentation] 上気道流体シミュレーションを用いた上顎骨急速拡大による歯科治療前後の吸気時咽頭気道圧の評価 (2012)
  • Author(s): 岩崎智憲, 齊藤一誠, 原田みずえ, 宮下圭一, 松根彰志, 武元嘉彦, 深水 篤, 佐藤秀夫, 稲田絵美, 長谷川大子, 覚野恵梨子,嘉ノ海龍三, 早崎治明, 黒野祐一, 山崎要一
  • Organizer: 第37回日本睡眠学会
  • Place of Presentation: 横浜市
  • Year and Date: 2012-06-29
• [Presentation] Improving tongue posture and pharynx airway as a side effect of rapid maxillary expansion in children: A cone-beam computed tomography study (2012)
  • Author(s): Iwasaki T, Saitoh I, Kanomi R, Hayasaki H, Yamasaki Y
  • Organizer: American Association of Orthodontists (AAO) 112th Annual Session
  • Place of Presentation: Honolulu
  • Year and Date: 2012-05-03
• [Presentation] Detection of specific obstruction sites using fluid-structure interaction analysis in children with obstructive sleep apnea syndrome (2011)
  • Author(s): Iwasaki T, Saitoh I, Harada M, Miyashita K, Matsune S, Takemoto Y, Inada E, Kanomi R, Hayasaki H, Kurono Y, Yamasaki Y
  • Organizer: World Sleep 2011
  • Place of Presentation: Kyoto, Japan, ICC Kyoto
  • Year and Date: 20111016-20
• [Presentation] 閉塞性睡眠時無呼吸症候群への上気道流体シミュレーションの臨床応用 (2011)
  • Author(s): 岩崎智憲,齊藤一誠,早崎治明,山崎要一
  • Organizer: 第27回「歯科医学を中心とした総合的な研究を推進する集い」
  • Place of Presentation: 東京都千代田区・日本歯科医師会館
  • Year and Date: 2011-01-08
• [Presentation] 上気道流体シミュレーションを用いた小児閉塞性睡眠時無呼吸症候群の通気障害部位の特定方法について (2010)
  • Author(s): 岩崎智憲, 早崎治明, 嘉ノ海龍三, 武元嘉彦, 齊藤一誠, 松根彰志, 黒野祐一, 山崎要一
  • Organizer: 第48回日本小児歯科学会大会
  • Place of Presentation: 名古屋市
  • Year and Date: 20100519-20
• [Presentation] Evaluation of upper airway obstruction in Class II children using fluid-mechanical simulation (2010)
  • Author(s): Iwasaki T, Kanomi R, Hayasaki H,Yamasaki Y
  • Organizer: American Association of Orthodontists (AAO) 110th Annual Session
  • Place of Presentation: Washington DC
  • Year and Date: 20100500