2012 Fiscal Year Final Research Report
Molecular biological investigation of periodontal ligament homeostasis in Slc39a13/Zip13 mice
| Project/Area Number |
22592302
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
IDAIRA Yayoi 鶴見大学, 歯学部, 学内講師 (40200018)
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| Co-Investigator(Kenkyū-buntansha) |
ASADA Yoshinobu 鶴見大学, 歯学部, 教授 (20184145)
SHIMODA Shinji 鶴見大学, 歯学部, 教授 (30139620)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 歯根膜 / 象牙質 / 歯槽骨 / 線維性結合組織 / 歯根 / Zip13,HE / TEM |
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| Research Abstract |
The aim of our study was to investigate the role of Zip13 in the metabolism of periodontalligament. To examine the biological role of Zip13, we performed the morphologicobservation for Achilles tendon and sagittal suture at the cranium which are comprised of fibrous connective tissue as well as periodontal ligament using H&E staining, silverimpregnation and transmission electron microscope (TEM) and immunostaining. Ourresults reveal Zip13 may play an important role to periodontal ligament homeostasis.
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