2012 Fiscal Year Final Research Report
Development of the bone substitute material for alveolar bone regeneration during tooth movement
| Project/Area Number |
22592306
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Osaka Dental University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
BABA Shunsuke 大阪歯科大学, 歯学部附属病院, 教授 (40275227)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 歯科矯正学 / 生体材料学 / 組織工学 / 人工コラーゲン |
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| Research Abstract |
Implantable scaffolds of the chemical synthesis of collagen model polypeptides consisting of a Pro-Hyp-Gly [poly(PHG)] sequence for tissue regeneration need to be biodegradable, have no ability to induce inflammation and to act as a scaffold for cell proliferation and differentiation. The combining poly(PHG) and alpha-tricalcium phosphate particles, or mesenchymal stem cells showed extremely rapid bone regeneration in a calvarial defect model in mini-pigs.
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[Journal Article] Evaluation of a 3-D, woven-fabric, composite scaffold using experimen tal canine models of bone defects inmandibles2011
Author(s)
Shunsuke Baba, Yoshiya Hashimoto, Takeomi Inoue, Daisuke Kimura, Saeko S umikura, Yumi Sonoda Yoichi Yamada, Kenji Ito, Masaki Hojo, Taiji Adach i.
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Journal Title
J Oral Tissue Engin
Volume: 8(3)
Pages: 212-221
Peer Reviewed
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