2012 Fiscal Year Final Research Report
Basic research on the influence of obesity, menopause, lymphatics, and honey on the clean healing of full-thickness cutaneous wounds
| Project/Area Number |
22592363
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Fundamental nursing
|
|---|
| Research Institution | Kanazawa University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
SUGAMA Junko 金沢大学, 保健学系, 教授 (00203307)
KONYA Chizuko 金沢医科大学, 看護学部, 教授 (20303282)
OKUWA Mayumi 金沢大学, 保健学系, 教授 (30303291)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 基礎看護学 / 看護技術 / 看護ケア / 皮膚創傷治癒 / 皮膚熱傷創 / 蜂蜜 / エストロゲン / プラズマ |
|---|
| Research Abstract |
We investigated factors that affect the healing of full-thickness cutaneous wounds in mice. Estrogen was effective for wound healing in ovariectomized mouse, but not in male mouse. There is room for further investigation on whether it is effective only in females. The effect of isoflavone on wound healing was not clear. It was also unclear whether obesity caused a delay of wound healing because the obese mice dramatically lost weight after wounding. It is thus necessary to re-examine models of obesity. Inhibition of lymphangiogenesis seemed to delay the healing. Since the effect of honey on wounds or burn wounds depended on the type of honey, it is necessary to evaluate several kinds of honey.
|
