2012 Fiscal Year Final Research Report
Synthesis of the bioactive fluorescent molecules: (inspired by pluramycins)
| Project/Area Number |
22603003
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
ケミカルバイオロジー
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
ANDO Yoshio 東京工業大学, 大学院・理工学研究科, 助教 (40532742)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 有機合成化学 / 天然物化学 |
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| Research Abstract |
Development of synthetic route to the total synthesis of pluramycins, was studied. The efficient ways for the bis-C-glycoside and aglycon synthesis were developed. These methodologies were successfully applied to the total synthesis of the saptomycin B, which is one of the pluramycins. This synthetic route would be expanded as a fundamental technology to the synthesis of pluramycin derivatives and the studies of chemicalbiology.
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