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2012 Fiscal Year Final Research Report

Development of high precision beam intensity control method for decreasing irradiation time in particle cancer therapy

Research Project

  • PDF
Project/Area Number 22611006
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical Physics/Radiological Technology
Research InstitutionGunma University

Principal Investigator

TORIKAI Kouta  群馬大学, 先端科学研究指導者育成ユニッ ト, 助教 (90443077)

Project Period (FY) 2010 – 2012
Keywords粒子線治療 / シンクロトロン / ビーム物理 / 加速制御 / パルス電圧
Research Abstract

This study aims for surveying ultra-fast beam extraction control method in synchrotron. A basic idea is proposed by K. Torikai et al. in 2009. The extracted beam by “third-resonance" has time structure, which contains strong beam intensity peak. The frequency of the peak is around 50Hz to 500Hz. The proposed method uses pulse-shape acceleration voltage in order to control the third-resonance condition andΔp/p.
In this study, a repetition rate of 6MHz, maximum pulse voltage of 100V, pulse-timing accuracy of 2nsec power supply is assembled. When this power supply is installed in synchrotron, it serves for turn-by-turn controlling beam current and On/Off of extraction. Beam circulation frequency in synchrotron for particle therapy is around few or several MHz, and this proposed method provides beam control of few 10 times faster than current control method. This method serves for shortening the irradiation time by 1/10,especially in layer-stacking irradiation method. The power supply, control software and simulation system was assembled through this study.

  • Research Products

    (9 results)

All 2013 2012 2011 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (2 results) Book (1 results) Remarks (1 results) Patent(Industrial Property Rights) (3 results)

  • [Journal Article] Beam range estimation by measuring bremsstrahlung2012

    • Author(s)
      Yamaguchi M, Torikai K, Kawachi N,Shimada H, Satoh T, Nagao Y, Fujimaki S, Kokubun M, Watanabe S, Takahashi T, Arakawa K, Kamiya T, Nakano T
    • Journal Title

      Phys Med Biol

      Volume: 21;57(10) Pages: 2843-56

    • Peer Reviewed
  • [Journal Article] a histone acetyltransferase inhibitor2012

    • Author(s)
      Oike T, Ogiwara H, Torikai K, Nakano T, Yokota J, Kohno T.Garcinol
    • Journal Title

      radiosensitizes cancer cells by inhibiting non-homologous end joining. Int J Radiat Oncol Biol Phys

      Volume: 1;84(3) Pages: 815-21

    • Peer Reviewed
  • [Presentation] Sub-mm Therapeutic Carbon-ion Irradiation Port In Gunma University2012

    • Author(s)
      Kota Torikai, Satoru Yamada, Tatsuaki Kanai, Eri Takeshita, Ken Yusa, Mutsumi Tashiro, Hirofumi Shimada, Takashi Nakano
    • Organizer
      International Conference on ParticleAccelerator Conference 2011
    • Place of Presentation
      クルーサル会議場(IPAC'11)(サンセバスチャン、スペイン)
    • Year and Date
      2012-09-08
  • [Presentation] 中野隆史腫瘍細胞密度の位置依存モデルによるTCP維持とCTV端での線量低減の両立可能性解析2011

    • Author(s)
      鳥飼幸太、加藤弘之、安藤興一、吉田由香里、金井達明
    • Organizer
      神戸ポートピアホテル会議場
    • Place of Presentation
      神戸市、兵庫県
    • Year and Date
      2011-11-18
  • [Book] 放射線外科 治療の進歩2012

    • Author(s)
      Textbook of Radiosurgery
    • Total Pages
      51-57
    • Publisher
      メディカ出版、井上洋編
  • [Remarks]

    • URL

      http://asrldu.dept.med.gunma-u.ac.jp/ktorikai/kouta_torikai.html

  • [Patent(Industrial Property Rights)] 冷却装置及び放射線検出装置2013

    • Inventor(s)
      中野隆史、鳥飼幸太、荒川和夫
    • Industrial Property Rights Holder
      群馬大学、株式会社テクノアソシエ
    • Industrial Property Number
      特許、特願2013-013272
    • Filing Date
      2013-01-28
  • [Patent(Industrial Property Rights)] 調剤管理システム2012

    • Inventor(s)
      鳥飼幸太、阿部正樹、岡正俊
    • Industrial Property Rights Holder
      群馬大学、トッパン・フォームズ株式会社
    • Industrial Property Number
      特許、特願20120242160
    • Filing Date
      2012-11-01
  • [Patent(Industrial Property Rights)] 粒子線モニタリング装置、粒子線モニ タリングプログラム及び粒子線モニタリン グ方法2012

    • Inventor(s)
      鳥飼幸太、阿部正樹、岡正俊
    • Industrial Property Rights Holder
      群馬大学、トッパン・フォームズ株式会社
    • Industrial Property Number
      特許、特願20120242160
    • Filing Date
      2012-11-01

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Published: 2014-08-29  

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