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2011 Fiscal Year Final Research Report

Development of ultra-low field multimodal MRI system

Research Project

  • PDF
Project/Area Number 22650116
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Medical systems
Research InstitutionKyoto University

Principal Investigator

KOBAYASHI Tetsuo  京都大学, 大学院・工学研究科, 教授 (40175336)

Co-Investigator(Renkei-kenkyūsha) OIDA Takenori  京都大学, 大学院・工学研究科, 助教 (70447910)
Project Period (FY) 2010 – 2011
Keywords原子磁気センサ / MRI / MCG / 光ポンピング / 医用イメージング / MEG
Research Abstract

In recent years, optically pumped atomic magnetometers(OPAMs) have reached sensitivities comparable to and even surpassing those of super-conducting quantum interference devices(SQUIDs). In this study, we developed an ultrahigh-sensitivity OPAM as a magnetic sensor for an ultra-low field(ULF) MRI system, which can measure biomagnetic fields and magnetic resonance(MR) signals simultaneously. First, we demonstrated that our newly developed K-Rb hyblid OPAM achieved high sensitivity. In addition, we demonstrated measurements of human magnetocardiograms with our OPAM. Finally, we successfully detected MR signals using the OPAM.

  • Research Products

    (20 results)

All 2012 2011 Other

All Journal Article (8 results) (of which Peer Reviewed: 7 results) Presentation (11 results) Remarks (1 results)

  • [Journal Article] A thermalnoise calculation method for precise estimation of signal-to-noise ratio of ULF-MRI2012

    • Author(s)
      Tatsuya Yamashita, Takenori Oida, Shoji Hamada and Tetsuo Kobayashi
    • Journal Title

      Journal of Magnetic Resonance

      Volume: Vol.215 Pages: 100-108

    • DOI

      DOI:10.1016/j.jmr.2012.01.015

    • Peer Reviewed
  • [Journal Article] Detecting rotating magnetic fields using optically pumped atomic magnetometers for measuring ultra-low-field magnetic resonance signals2012

    • Author(s)
      Takenori Oida, Yosuke Ito, Keigo Kamada and Tetsuo Kobayashi
    • Journal Title

      Journal of Magnetic Resonance

      Volume: Vol.217 Pages: 6-9

    • DOI

      DOI:10.1016/j.jmr.2011.12.014

    • Peer Reviewed
  • [Journal Article] 光ポンピング原子磁気センサを用いたMR信号検出のための磁場分布解析2012

    • Author(s)
      土田昌宏, 笈田武範、小林哲生
    • Journal Title

      電気学会論文誌A

      Volume: Vol.132、No.3 Pages: 220-226

    • URL

      http://dx.doi.org/10.1541/ieejfms.132.220

    • Peer Reviewed
  • [Journal Article] Magnetic field mapping and biaxialvetor operation for biomagnetic appicationsusing high-sensitivity optically pumpedatomic magnetometers2011

    • Author(s)
      Shuji Taue, Yasuyuki Sugihara, Tetsuo Kobayashi, Kiyoshi Ishikawa and Keigo Kamada
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: Vol.50 Pages: 11604-1-7

    • DOI

      DOI:10.1143/JJAP

    • Peer Reviewed
  • [Journal Article] Sensitivity improvement of spin-exchange relaxation free atomic magnetometers by hybrid optical pumping of potassium and rubidium2011

    • Author(s)
      Yousuke Ito, Hiroyuki Ohnishi, Keigo Kamada, Tetsuo Kobayashi
    • Journal Title

      IEEE Transactions on Magnetics

      Volume: Vol.47, No.10 Pages: 3550-3553

    • DOI

      DOI:10.1109/TMAG.2011.2148191

    • Peer Reviewed
  • [Journal Article] Optimization of flux transformer for ultra-low field MRI systems with optically pumped atomic magnetometers2011

    • Author(s)
      Takenori Oida, Yuta Kawamura and Tetsuo Kobayashi
    • Journal Title

      IEEE Transactions on Magnetics

      Volume: Vol.47, No.10 Pages: 3074-3077

    • DOI

      DOI:10.1109/TMAG.2011.2156765

    • Peer Reviewed
  • [Journal Article] Pump laser power dependent bandwidth and sensitivity of optically pumped atomic magnetometers2011

    • Author(s)
      Keigo Kamada, Shuji Taue, Tetsuo Kobayashi
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: Vol.50 Pages: 056602-1-7

    • DOI

      DOI:10.1143/JJAP.50.056602

    • Peer Reviewed
  • [Journal Article] 高感度光ポンピング原子磁気センサ2011

    • Author(s)
      小林哲生
    • Journal Title

      応用物理学会誌

      Volume: Vol.80, No.3 Pages: 211-215

    • URL

      http://www.jsap.or.jp/ap/2011/ob8003/p800211.html

  • [Presentation] 光ポンピング原子磁気センサにおける2光軸型配置と1光軸配置の実験的比較2012

    • Author(s)
      市原 直、鎌田啓吾, 伊藤陽介、水谷夏彦、小林哲生
    • Organizer
      第59回応用物理学関係連合講演会
    • Place of Presentation
      東京
    • Year and Date
      20120315-18
  • [Presentation] K-Rbハイブリッドセルを用いた光ポンピング原子磁気センサにおけるポンプ光強度の減衰に伴う磁場応答の変化2012

    • Author(s)
      伊藤陽介、大西宏征、鎌田啓吾、小林哲生
    • Organizer
      第59回応用物理学関係連合講演会
    • Place of Presentation
      東京
    • Year and Date
      20120315-18
  • [Presentation] 超低磁場マルチモダリティMRIを目指した原子磁気センサによりMR信号の遠隔計測2011

    • Author(s)
      笈田武範、河村雄太、鎌田啓吾, 伊藤陽介、小林哲生
    • Organizer
      第39回日本磁気共鳴医学会大会
    • Place of Presentation
      小倉
    • Year and Date
      20110929-1001
  • [Presentation] 光ポンピング原子磁気センサを用いたMR信号検出のための磁場分布解析2011

    • Author(s)
      大西宏征、伊藤陽介、鎌田啓吾, 小林哲生
    • Organizer
      平成23年電気学会基礎・材料・共通部門大会
    • Place of Presentation
      東京
    • Year and Date
      20110921-22
  • [Presentation] K-Rbハイブリッドセルを用いた光ポンピング原子磁気センサの基礎的検討2011

    • Author(s)
      大西宏征、伊藤陽介、鎌田啓吾, 小林哲生
    • Organizer
      2011年秋季第72回応用物理学会学術講演会
    • Place of Presentation
      山形
    • Year and Date
      20110829-0902
  • [Presentation] K-Rbハイブリッドセルを用いた光ポンピング原子磁気センサの周波数特性2011

    • Author(s)
      伊藤陽介、大西宏征、鎌田啓吾, 小林哲生
    • Organizer
      2011年秋季第72回応用物理学会学術講演会
    • Place of Presentation
      山形
    • Year and Date
      20110829-0902
  • [Presentation] Optically pumped atomic magnetometer toward ultra-low field MRI systems2011

    • Author(s)
      Tetsuo Kobayashi
    • Organizer
      Black Forest Focus on Soft Matter
    • Place of Presentation
      Freiburg, Germany
    • Year and Date
      20110726-29
  • [Presentation] 超高感度光ポンピング原子磁気センサによるヒト心磁図の計測2011

    • Author(s)
      鎌田啓吾、伊藤陽介、小林哲生
    • Organizer
      電子情報通信学会MEとバイオサイバネティクス研究会
    • Place of Presentation
      徳島
    • Year and Date
      20110708-09
  • [Presentation] Sensitivity improvement of spin-exchange relaxation free atomic magnetometers by hybrid optical pumping of potassium and rubidium2011

    • Author(s)
      Yousuke Ito, Hiroyuki Ohnishi, Keigo Kamada, Tetsuo Kobayashi
    • Organizer
      Intermag 2011
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      20110425-29
  • [Presentation] Optimization of flux transformer for ultra-low field MRI systems with optically pumped atomic magnetometers2011

    • Author(s)
      Takenori Oida, Yuta Kawamura and Tetsuo Kobayashi
    • Organizer
      Intermag 2011
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      20110425-29
  • [Presentation] 原子磁気センサを用いた生体熱雑音磁場計測の理論的検討2011

    • Author(s)
      山下達也、笈田武範、濱田昌司、小林哲生
    • Organizer
      電子情報通信学会MEとバイオサイバネティクス研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-12-20
  • [Remarks]

    • URL

      http://bfe.kuee.kyoto-u.ac.jp/publications03.html

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Published: 2013-07-31  

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